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    KLC2 kinesin light chain 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 518136, updated on 1-Jan-2025

    Summary

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    Official Symbol
    KLC2provided by VGNC
    Official Full Name
    kinesin light chain 2provided by VGNC
    Primary source
    VGNC:VGNC:30623
    See related
    BGD:BT19936; Ensembl:ENSBTAG00000019334
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See KLC2 in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (44313711..44323510)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene phosphofurin acidic cluster sorting protein 1 Neighboring gene uncharacterized LOC132344208 Neighboring gene large ribosomal subunit protein uL23-like Neighboring gene uncharacterized LOC107131974 Neighboring gene RAB1B, member RAS oncogene family Neighboring gene cornichon family AMPA receptor auxiliary protein 2 Neighboring gene Yip1 interacting factor homolog A, membrane trafficking protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC143149

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables kinesin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of kinesin complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    kinesin light chain 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075768.1 → NP_001069236.1  kinesin light chain 2

      See identical proteins and their annotated locations for NP_001069236.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123748
      UniProtKB/TrEMBL
      A0AAA9S260, Q08DH4
      Related
      ENSBTAP00000076175.1, ENSBTAT00000099464.1
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      44313711..44323510
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005227099.5 → XP_005227156.1  kinesin light chain 2 isoform X1

      See identical proteins and their annotated locations for XP_005227156.1

      UniProtKB/TrEMBL
      A0AAA9S260, F6R262
      Related
      ENSBTAP00000025752.6, ENSBTAT00000025752.7
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    2. XM_005227098.5 → XP_005227155.1  kinesin light chain 2 isoform X1

      See identical proteins and their annotated locations for XP_005227155.1

      UniProtKB/TrEMBL
      A0AAA9S260, F6R262
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    3. XM_024987155.2 → XP_024842923.1  kinesin light chain 2 isoform X2

      UniProtKB/TrEMBL
      A0AAA9S260, Q08DH4
      Related
      ENSBTAP00000091341.1, ENSBTAT00000129971.1
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    4. XM_005227096.3 → XP_005227153.1  kinesin light chain 2 isoform X1

      See identical proteins and their annotated locations for XP_005227153.1

      UniProtKB/TrEMBL
      A0AAA9S260, F6R262
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    5. XM_005227100.3 → XP_005227157.1  kinesin light chain 2 isoform X2

      See identical proteins and their annotated locations for XP_005227157.1

      UniProtKB/TrEMBL
      A0AAA9S260, Q08DH4
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    6. XM_005227097.5 → XP_005227154.1  kinesin light chain 2 isoform X1

      See identical proteins and their annotated locations for XP_005227154.1

      UniProtKB/TrEMBL
      A0AAA9S260, F6R262
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
      cl25732
      Location:9 → 139
      SMC_N; RecF/RecN/SMC N terminal domain

    7. XM_010821089.3 → XP_010819391.1  kinesin light chain 2 isoform X3

      UniProtKB/TrEMBL
      A0AAA9S260
      Conserved Domains (4) summary
      sd00006
      Location:282 → 310
      TPR; TPR repeat [structural motif]
      pfam13374
      Location:281 → 322
      TPR_10; Tetratricopeptide repeat
      pfam13424
      Location:236 → 314
      TPR_12; Tetratricopeptide repeat
      cl19252
      Location:76 → 150
      MreC; rod shape-determining protein MreC
    Nucleotide Protein Strain
    Heading Accession and Version

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