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    MIER2 MIER family member 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 523726, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MIER2provided by VGNC
    Official Full Name
    MIER family member 2provided by VGNC
    Primary source
    VGNC:VGNC:31470
    See related
    BGD:BT20869; Ensembl:ENSBTAG00000019767
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See MIER2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (43033674..43056701, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene histone deacetylase 5-like Neighboring gene phospholipid phosphatase 2 Neighboring gene theg spermatid protein Neighboring gene C2 calcium dependent domain containing 4C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC157251

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables histone deacetylase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transcription corepressor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mesoderm induction early response protein 2
    Names
    mi-er2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099026.2 → NP_001092496.1  mesoderm induction early response protein 2

      See identical proteins and their annotated locations for NP_001092496.1

      Status: PROVISIONAL

      Source sequence(s)
      BC142273
      UniProtKB/Swiss-Prot
      A5PJX4
      UniProtKB/TrEMBL
      A0A3Q1M7K5
      Related
      ENSBTAP00000066371.2, ENSBTAT00000087313.2
      Conserved Domains (3) summary
      smart00717
      Location:301 → 347
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:302 → 346
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:197 → 247
      ELM2; ELM2 domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43033674..43056701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015472192.3 → XP_015327678.1  mesoderm induction early response protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M438, A0A3Q1M7K5
      Related
      ENSBTAP00000062989.2, ENSBTAT00000081935.2
      Conserved Domains (3) summary
      smart00717
      Location:301 → 347
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd11661
      Location:302 → 346
      SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
      pfam01448
      Location:197 → 247
      ELM2; ELM2 domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A5PJX4.1 GenPept UniProtKB/Swiss-Prot:A5PJX4

    Gene LinkOut

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