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    VIM vimentin [ Bos taurus (domestic cattle) ]

    Gene ID: 280955, updated on 27-Dec-2024

    Summary

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    Official Symbol
    VIMprovided by VGNC
    Official Full Name
    vimentinprovided by VGNC
    Primary source
    VGNC:VGNC:36796
    See related
    BGD:BT11168; Ensembl:ENSBTAG00000018463
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See VIM in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (31653816..31661745)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene cubilin Neighboring gene tRNA aspartic acid methyltransferase 1 Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Neighboring gene 3-hydroxyacyl-CoA dehydratase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Dynamic expression of vimentin in bovine blastocysts in extended in vitro culture. Ikeda S, et al. Reprod Domest Anim, 2010 Apr. PMID 19019059
    2. Disassembly of the vimentin cytoskeleton disrupts articular cartilage chondrocyte homeostasis. Blain EJ, et al. Matrix Biol, 2006 Sep. PMID 16876394
    3. Nucleotide sequence of the bovine vimentin-encoding cDNA. Hess JF, et al. Gene, 1994 Mar 25. PMID 8144034
    4. A possible role of vimentin on the cell surface for the activation of latent transforming growth factor-beta. Nishida Y, et al. FEBS Lett, 2009 Jan 22. PMID 19121313
    5. Identification of differentially expressed genes in individual bovine preimplantation embryos produced by nuclear transfer: improper reprogramming of genes required for development. Pfister-Genskow M, et al. Biol Reprod, 2005 Mar. PMID 15483223

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Immunocytochemistry for Vimentin detection in nuclei of IVF and NT bovine embryos
      Title: Identification of differentially expressed genes in individual bovine preimplantation embryos produced by nuclear transfer: improper reprogramming of genes required for development.
    2. These results indicate that the inner mass differentiates dynamically in blastocysts, as reflected by the expression of vimentin; higher vimentin expression may reflect the higher developmental competence of embryos.
      Title: Dynamic expression of vimentin in bovine blastocysts in extended in vitro culture.
    3. an intact vimentin intermediate filament network contributes to the maintenance of the chondrocyte phenotype
      Title: Disassembly of the vimentin cytoskeleton disrupts articular cartilage chondrocyte homeostasis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC139781

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables structural constituent of cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intermediate filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vimentin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173969.3 → NP_776394.2  vimentin

      See identical proteins and their annotated locations for NP_776394.2

      Status: PROVISIONAL

      Source sequence(s)
      BC118269
      UniProtKB/Swiss-Prot
      P48616, Q17QM7
      Related
      ENSBTAP00000024572.3, ENSBTAT00000024572.4
      Conserved Domains (2) summary
      pfam00038
      Location:102 → 410
      Filament; Intermediate filament protein
      pfam04732
      Location:14 → 101
      Filament_head; Intermediate filament head (DNA binding) region

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      31653816..31661745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48616.3 GenPept UniProtKB/Swiss-Prot:P48616

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.