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    MAPK14 mitogen-activated protein kinase 14 [ Bos taurus (domestic cattle) ]

    Gene ID: 534492, updated on 29-Jan-2025

    Summary

    Official Symbol
    MAPK14provided by VGNC
    Official Full Name
    mitogen-activated protein kinase 14provided by VGNC
    Primary source
    VGNC:VGNC:31216
    See related
    BGD:BT11558; Ensembl:ENSBTAG00000020783
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    p38
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See MAPK14 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (9970264..10045594)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene SRSF protein kinase 1 Neighboring gene transcription factor E2F5-like Neighboring gene U6 spliceosomal RNA Neighboring gene solute carrier family 26 member 8 Neighboring gene mitogen-activated protein kinase 13 Neighboring gene bromodomain and PHD finger containing 3

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC142910

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables MAP kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in p38MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    mitogen-activated protein kinase 14
    NP_001095644.1
    XP_010816425.1
    XP_010816426.1
    XP_015315258.1
    XP_059736373.1
    XP_059736374.1
    XP_059736375.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102174.1NP_001095644.1  mitogen-activated protein kinase 14

      See identical proteins and their annotated locations for NP_001095644.1

      Status: PROVISIONAL

      Source sequence(s)
      BC148063
      UniProtKB/TrEMBL
      A0A3Q1M517, A6QLR9, F6PU21
      Conserved Domains (1) summary
      cd07877
      Location:6350
      STKc_p38alpha; Catalytic domain of the Serine/Threonine Kinase, p38alpha Mitogen-Activated Protein Kinase (also called MAPK14)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      9970264..10045594
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010818123.3XP_010816425.1  mitogen-activated protein kinase 14 isoform X1

      See identical proteins and their annotated locations for XP_010816425.1

      UniProtKB/TrEMBL
      A0A3Q1LTT9, A0A3Q1M517
      Related
      ENSBTAP00070013627.1, ENSBTAT00070023151.1
      Conserved Domains (1) summary
      cd07877
      Location:6350
      STKc_p38alpha; Catalytic domain of the Serine/Threonine Kinase, p38alpha Mitogen-Activated Protein Kinase (also called MAPK14)
    2. XM_059880390.1XP_059736373.1  mitogen-activated protein kinase 14 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M517
      Related
      ENSBTAP00070013617.1, ENSBTAT00070023132.1
    3. XM_059880392.1XP_059736375.1  mitogen-activated protein kinase 14 isoform X6

      UniProtKB/TrEMBL
      A0AAA9T8X7
      Related
      ENSBTAP00070013607.1, ENSBTAT00070023116.1
    4. XM_015459772.3XP_015315258.1  mitogen-activated protein kinase 14 isoform X2

      Conserved Domains (2) summary
      smart00220
      Location:24253
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:6254
      PKc_like; Protein Kinases, catalytic domain
    5. XM_059880391.1XP_059736374.1  mitogen-activated protein kinase 14 isoform X5

    6. XM_010818124.4XP_010816426.1  mitogen-activated protein kinase 14 isoform X4

      UniProtKB/TrEMBL
      A0A3Q1M517
      Conserved Domains (1) summary
      cl21453
      Location:6316
      PKc_like; Protein Kinases, catalytic domain