ADAM9 ADAM metallopeptidase domain 9 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: ADAM9provided by VGNC
Official Full Name: ADAM metallopeptidase domain 9provided by VGNC
Primary source: VGNC:VGNC:25613
See related: BGD:BT24917
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 27

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	27	NC_037354.1 (34152261..34242502)

Chromosome 27 - NC_037354.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables integrin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables metalloendopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell-cell adhesion mediated by integrin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in membrane protein ectodomain proteolysis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transforming growth factor beta receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: disintegrin and metalloproteinase domain-containing protein 9

Names: a disintegrin and metalloproteinase domain 9 (meltrin gamma)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001192818.3 → NP_001179747.2 disintegrin and metalloproteinase domain-containing protein 9 precursor

Status: VALIDATED

Source sequence(s)

DAAA02060867

Conserved Domains (5) summary

smart00608
Location:500 → 637

ACR; ADAM Cysteine-Rich Domain

cd04269
Location:212 → 404

ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...

pfam00200
Location:423 → 497

Disintegrin; Disintegrin

pfam01421
Location:212 → 406

Reprolysin; Reprolysin (M12B) family zinc metalloprotease

pfam01562
Location:55 → 160

Pep_M12B_propep; Reprolysin family propeptide