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    LCP1 lymphocyte cytosolic protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 540990, updated on 30-Jan-2025

    Summary

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    Official Symbol
    LCP1provided by VGNC
    Official Full Name
    lymphocyte cytosolic protein 1provided by VGNC
    Primary source
    VGNC:VGNC:30817
    See related
    BGD:BT26241; EnsemblRapid:ENSBTAG00070026057
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LCP1 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (16207300..16312292, complement)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 13 Neighboring gene carboxypeptidase B2 Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene heterogeneous nuclear ribonucleoprotein D-like Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene uncharacterized LOC112449177 Neighboring gene leucine rich repeat containing 63 Neighboring gene rubicon like autophagy enhancer

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128288

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament network formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin filament IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin filament bundle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plastin-2
    Names
    lymphocyte cytosolic protein 1 (L-plastin)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034720.2 → NP_001029892.1  plastin-2

      See identical proteins and their annotated locations for NP_001029892.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103001
      UniProtKB/TrEMBL
      A0A3Q1LSN0, Q3ZC00
      Related
      ENSBTAP00070035033.1, ENSBTAT00070059020.1
      Conserved Domains (5) summary
      smart00033
      Location:398 → 501
      CH; Calponin homology domain
      COG5069
      Location:16 → 620
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00014
      Location:121 → 236
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00307
      Location:265 → 370
      CH; Calponin homology (CH) domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      16207300..16312292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005213674.5 → XP_005213731.1  plastin-2 isoform X1

      See identical proteins and their annotated locations for XP_005213731.1

      UniProtKB/TrEMBL
      A0A3Q1LSN0
      Conserved Domains (5) summary
      smart00033
      Location:398 → 501
      CH; Calponin homology domain
      COG5069
      Location:16 → 620
      SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
      cd00014
      Location:121 → 236
      CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
      cd00051
      Location:13 → 79
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00307
      Location:265 → 370
      CH; Calponin homology (CH) domain

    2. XM_059892108.1 → XP_059748091.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LSN0

    3. XM_059892110.1 → XP_059748093.1  plastin-2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LSN0
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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