U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TYMS thymidylate synthetase [ Bos taurus (domestic cattle) ]

    Gene ID: 507631, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TYMSprovided by VGNC
    Official Full Name
    thymidylate synthetaseprovided by VGNC
    Primary source
    VGNC:VGNC:36549
    See related
    BGD:BT27747; Ensembl:ENSBTAG00000007003
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TS
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TYMS in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 24 NC_037351.1 (35553506..35564151)

    Chromosome 24 - NC_037351.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112444249 Neighboring gene clusterin like 1 Neighboring gene enolase superfamily member 1 Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase Neighboring gene adenylate cyclase activating polypeptide 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037351.1 Chromosome 24 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Estimate of nucleotide diversity in dogs with a pool-and-sequence method. Brouillette JA, et al. Mamm Genome, 2000 Dec. PMID 11130975
    2. Seven genes from human chromosome 18 map to chromosome 24 in the bovine. Larsen NJ, et al. Cytogenet Cell Genet, 1996. PMID 8697804
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC134366

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables thymidylate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dTMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    thymidylate synthase
    Names
    TSase
    NP_001032905.1
    XP_010817120.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037816.1 → NP_001032905.1  thymidylate synthase

      See identical proteins and their annotated locations for NP_001032905.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111139
      UniProtKB/Swiss-Prot
      Q2TA32, Q9N1D3
      Related
      ENSBTAP00000009214.3, ENSBTAT00000009214.5
      Conserved Domains (1) summary
      pfam00303
      Location:35 → 354
      Thymidylat_synt; Thymidylate synthase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037351.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      35553506..35564151
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010818818.3 → XP_010817120.1  thymidylate synthase isoform X1

      UniProtKB/TrEMBL
      A0AAA9SJR7, A0AAA9TIK9
      Related
      ENSBTAP00000098145.1, ENSBTAT00000133947.1
      Conserved Domains (1) summary
      pfam00303
      Location:35 → 316
      Thymidylat_synt; Thymidylate synthase
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2TA32.1 GenPept UniProtKB/Swiss-Prot:Q2TA32

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials