U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MARCHF2 membrane associated ring-CH-type finger 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 508949, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MARCHF2provided by VGNC
    Official Full Name
    membrane associated ring-CH-type finger 2provided by VGNC
    Primary source
    VGNC:VGNC:31238
    See related
    BGD:BT25722; Ensembl:ENSBTAG00000021036
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    MARCH2; RNF172
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MARCHF2 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (17038303..17052944)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132345705 Neighboring gene angiopoietin like 4 Neighboring gene RAB11B, member RAS oncogene family Neighboring gene heterogeneous nuclear ribonucleoprotein M Neighboring gene PML-RARA regulated adaptor molecule 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Clone Names

    • MGC133913

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    E3 ubiquitin-protein ligase MARCHF2
    Names
    E3 ubiquitin-protein ligase MARCH2
    MARCH-II
    RING finger protein 172
    RING-type E3 ubiquitin transferase MARCH2
    RING-type E3 ubiquitin transferase MARCHF2
    membrane-associated RING finger protein 2
    membrane-associated RING-CH protein II
    membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
    NP_001032678.1
    XP_005208918.1
    XP_024849820.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037589.1 → NP_001032678.1  E3 ubiquitin-protein ligase MARCHF2

      Status: PROVISIONAL

      Source sequence(s)
      BC109744
      UniProtKB/Swiss-Prot
      Q32L65
      Related
      ENSBTAP00000028017.4, ENSBTAT00000028017.4
      Conserved Domains (2) summary
      pfam00558
      Location:172 → 199
      Vpu; Vpu protein
      cd16808
      Location:62 → 113
      RING_CH-C4HC3_MARCH2; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH2 (MARCH2)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      17038303..17052944
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024994052.2 → XP_024849820.1  E3 ubiquitin-protein ligase MARCHF2 isoform X1

      UniProtKB/TrEMBL
      A0A452DJW0
      Conserved Domains (2) summary
      pfam00558
      Location:239 → 266
      Vpu; Vpu protein
      cd16808
      Location:129 → 180
      RING_CH-C4HC3_MARCH2; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH2 (MARCH2)

    2. XM_005208861.5 → XP_005208918.1  E3 ubiquitin-protein ligase MARCHF2 isoform X2

      UniProtKB/Swiss-Prot
      Q32L65
      Conserved Domains (2) summary
      pfam00558
      Location:172 → 199
      Vpu; Vpu protein
      cd16808
      Location:62 → 113
      RING_CH-C4HC3_MARCH2; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING-CH2 (MARCH2)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32L65.1 GenPept UniProtKB/Swiss-Prot:Q32L65

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials