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    CD53 CD53 molecule [ Bos taurus (domestic cattle) ]

    Gene ID: 505040, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CD53provided by VGNC
    Official Full Name
    CD53 moleculeprovided by VGNC
    Primary source
    VGNC:VGNC:27039
    See related
    BGD:BT16064; Ensembl:ENSBTAG00000006466
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CD53 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (32494131..32532967, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene ligand dependent nuclear receptor interacting factor 1 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene potassium voltage-gated channel subfamily A member 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Analysis of bovine mammary gland EST and functional annotation of the Bos taurus gene index. Sonstegard TS, et al. Mamm Genome, 2002 Jul. PMID 12140684
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC137765

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leukocyte surface antigen CD53
    Names
    CD53 antigen
    cell surface glycoprotein CD53

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034232.2 → NP_001029404.1  leukocyte surface antigen CD53

      See identical proteins and their annotated locations for NP_001029404.1

      Status: PROVISIONAL

      Source sequence(s)
      BC113322
      UniProtKB/Swiss-Prot
      Q58DM3
      Related
      ENSBTAP00000008479.3, ENSBTAT00000008479.5
      Conserved Domains (2) summary
      cl02781
      Location:104 → 186
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:9 → 210
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      32494131..32532967 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015463652.3 → XP_015319138.1  leukocyte surface antigen CD53 isoform X1

      Conserved Domains (1) summary
      cl02781
      Location:85 → 161
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...

    2. XM_015463653.3 → XP_015319139.1  leukocyte surface antigen CD53 isoform X2

      Conserved Domains (1) summary
      pfam00335
      Location:9 → 163
      Tetraspannin; Tetraspanin family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58DM3.1 GenPept UniProtKB/Swiss-Prot:Q58DM3

    Gene LinkOut

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