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    LGI4 leucine rich repeat LGI family member 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 618195, updated on 27-Dec-2024

    Summary

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    Official Symbol
    LGI4provided by VGNC
    Official Full Name
    leucine rich repeat LGI family member 4provided by VGNC
    Primary source
    VGNC:VGNC:30859
    See related
    Ensembl:ENSBTAG00000017814
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LGI4 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (45851472..45862103, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene hepsin Neighboring gene FXYD domain containing ion transport regulator 3 Neighboring gene FXYD domain containing ion transport regulator 1 Neighboring gene FXYD domain containing ion transport regulator 7 Neighboring gene FXYD domain containing ion transport regulator 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC160066

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in myelination in peripheral nervous system IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuron maturation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat LGI family member 4
    Names
    leucine-rich glioma inactivated protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001103301.1 → NP_001096771.1  leucine-rich repeat LGI family member 4 precursor

      See identical proteins and their annotated locations for NP_001096771.1

      Status: PROVISIONAL

      Source sequence(s)
      BC147920
      UniProtKB/TrEMBL
      A6QLD0, A6QPY7, F1MTD1
      Related
      ENSBTAP00000025189.5, ENSBTAT00000025189.6
      Conserved Domains (6) summary
      smart00082
      Location:159 → 207
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:54 → 78
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:30 → 50
      LRR_RI; leucine-rich repeat [structural motif]
      pfam03736
      Location:397 → 439
      EPTP; EPTP domain
      pfam12799
      Location:102 → 141
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:77 → 137
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      45851472..45862103 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876951.1 → XP_059732934.1  leucine-rich repeat LGI family member 4 isoform X1

    2. XM_010814812.4 → XP_010813114.1  leucine-rich repeat LGI family member 4 isoform X1

      See identical proteins and their annotated locations for XP_010813114.1

      Conserved Domains (3) summary
      smart00082
      Location:101 → 149
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:93 → 105
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:339 → 381
      EPTP; EPTP domain

    3. XM_010814813.4 → XP_010813115.1  leucine-rich repeat LGI family member 4 isoform X1

      See identical proteins and their annotated locations for XP_010813115.1

      Conserved Domains (3) summary
      smart00082
      Location:101 → 149
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:93 → 105
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:339 → 381
      EPTP; EPTP domain

    4. XM_015458073.3 → XP_015313559.1  leucine-rich repeat LGI family member 4 isoform X1

      Conserved Domains (3) summary
      smart00082
      Location:101 → 149
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:93 → 105
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:339 → 381
      EPTP; EPTP domain
    Nucleotide Protein Strain
    Heading Accession and Version

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