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    PMPCA peptidase, mitochondrial processing subunit alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 767847, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PMPCAprovided by VGNC
    Official Full Name
    peptidase, mitochondrial processing subunit alphaprovided by VGNC
    Primary source
    VGNC:VGNC:33075
    See related
    BGD:BT18084; Ensembl:ENSBTAG00000001353
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PMPCA in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (103865177..103875087)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene caspase recruitment domain family member 9 Neighboring gene small nuclear RNA activating complex polypeptide 4 Neighboring gene endosome associated trafficking regulator 1 Neighboring gene inositol polyphosphate-5-phosphatase E Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC139568

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein processing involved in protein targeting to mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitochondrial-processing peptidase subunit alpha
    Names
    alpha-MPP
    inactive zinc metalloprotease alpha
    peptidase (mitochondrial processing) alpha
    peptidase, mitochondrial processing alpha subunit
    NP_001070432.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076964.1 → NP_001070432.1  mitochondrial-processing peptidase subunit alpha precursor

      See identical proteins and their annotated locations for NP_001070432.1

      Status: PROVISIONAL

      Source sequence(s)
      BC119849
      UniProtKB/Swiss-Prot
      Q0P5M8
      UniProtKB/TrEMBL
      A0AAA9S041
      Related
      ENSBTAP00000001782.3, ENSBTAT00000001782.5
      Conserved Domains (3) summary
      COG0612
      Location:65 → 504
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]
      pfam00675
      Location:77 → 226
      Peptidase_M16; Insulinase (Peptidase family M16)
      pfam05193
      Location:232 → 431
      Peptidase_M16_C; Peptidase M16 inactive domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      103865177..103875087
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0P5M8.1 GenPept UniProtKB/Swiss-Prot:Q0P5M8

    Gene LinkOut

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