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    PRPF3 pre-mRNA processing factor 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 510322, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PRPF3provided by VGNC
    Official Full Name
    pre-mRNA processing factor 3provided by VGNC
    Primary source
    VGNC:VGNC:33373
    See related
    BGD:BT21434; Ensembl:ENSBTAG00000013946
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PRPF3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (20311990..20330626, complement)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene threonyl-tRNA synthetase 2, mitochondrial Neighboring gene regulation of nuclear pre-mRNA domain containing 2 Neighboring gene protein-L-histidine N-pros-methyltransferase-like Neighboring gene microRNA mir-12064 Neighboring gene mitochondrial ribosomal protein S21

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC137653

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    U4/U6 small nuclear ribonucleoprotein Prp3
    Names
    PRP3 pre-mRNA processing factor 3 homolog
    pre-mRNA-splicing factor 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046051.2 → NP_001039516.1  U4/U6 small nuclear ribonucleoprotein Prp3

      See identical proteins and their annotated locations for NP_001039516.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112709
      UniProtKB/Swiss-Prot
      Q2KIA6
      UniProtKB/TrEMBL
      A0A3Q1MP00
      Related
      ENSBTAP00000018533.3, ENSBTAT00000018533.5
      Conserved Domains (3) summary
      smart00311
      Location:3 → 73
      PWI; PWI, domain in splicing factors
      pfam06544
      Location:546 → 673
      DUF1115; Protein of unknown function (DUF1115)
      pfam08572
      Location:309 → 521
      PRP3; pre-mRNA processing factor 3 (PRP3)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      20311990..20330626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005203870.5 → XP_005203927.1  U4/U6 small nuclear ribonucleoprotein Prp3 isoform X1

      See identical proteins and their annotated locations for XP_005203927.1

      UniProtKB/TrEMBL
      A0A3Q1MP00, F2Z4C4
      Related
      ENSBTAP00000066951.2, ENSBTAT00000083022.2
      Conserved Domains (3) summary
      smart00311
      Location:3 → 73
      PWI; domain in splicing factors
      pfam06544
      Location:546 → 673
      DUF1115; Protein of unknown function (DUF1115)
      pfam08572
      Location:308 → 521
      PRP3; pre-mRNA processing factor 3 (PRP3)

    2. XM_059883297.1 → XP_059739280.1  U4/U6 small nuclear ribonucleoprotein Prp3 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KIA6.1 GenPept UniProtKB/Swiss-Prot:Q2KIA6

    Gene LinkOut

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