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    CCL8 chemokine (C-C motif) ligand 8 [ Bos taurus (domestic cattle) ]

    Gene ID: 281044, updated on 1-Jan-2025

    Summary

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    Gene symbol
    CCL8
    Gene description
    chemokine (C-C motif) ligand 8
    See related
    BGD:BT10138
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    SCYA8
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    Genomic context

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    See CCL8 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (15807708..15809743, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein eL22-like Neighboring gene C-C motif chemokine ligand 1 Neighboring gene chemokine (C-C motif) ligand 11 Neighboring gene chemokine (C-C motif) ligand 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Cloning of the gene for bovine monocyte chemoattractant protein-2. Wempe F, et al. DNA Cell Biol, 1994 Jan. PMID 8286035
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chemokine activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in eosinophil chemotaxis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-C motif chemokine 8
    Names
    C-C motif chemokine 8-like
    MCP-2
    monocyte chemoattractant protein 2
    monocyte chemotactic protein 2
    small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
    small-inducible cytokine A8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174007.1 → NP_776432.1  C-C motif chemokine 8 precursor

      See identical proteins and their annotated locations for NP_776432.1

      Status: PROVISIONAL

      Source sequence(s)
      S67954
      UniProtKB/Swiss-Prot
      A5PJH3, Q09141, Q95MD5
      Conserved Domains (1) summary
      pfam00048
      Location:33 → 88
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      15807708..15809743 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09141.1 GenPept UniProtKB/Swiss-Prot:Q09141

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