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    CHD2 chromodomain helicase DNA binding protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 535026, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CHD2provided by VGNC
    Official Full Name
    chromodomain helicase DNA binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:27278
    See related
    BGD:BT16199; Ensembl:ENSBTAG00000017776
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CHD2 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 21 NC_037348.1 (14043709..14155872, complement)

    Chromosome 21 - NC_037348.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL29 Neighboring gene repulsive guidance molecule BMP co-receptor a Neighboring gene uncharacterized LOC132343330 Neighboring gene adenosine 5'-monophosphoramidase HINT1-like Neighboring gene BTB/POZ domain-containing protein KCTD2-like Neighboring gene uncharacterized LOC132343406 Neighboring gene family with sequence similarity 174 member B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037348.1 Chromosome 21 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC148727, MGC159952

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ATP-dependent chromatin remodeler activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nucleosome organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    chromodomain-helicase-DNA-binding protein 2
    NP_001095651.2
    XP_059735106.1
    XP_059735107.1
    XP_059735108.1
    XP_059735109.1
    XP_059735110.1
    XP_059735111.1
    XP_059735112.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102181.2 → NP_001095651.2  chromodomain-helicase-DNA-binding protein 2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000021
      UniProtKB/TrEMBL
      G3MXX3
      Related
      ENSBTAP00000054394.3, ENSBTAT00000065179.3
      Conserved Domains (6) summary
      PLN03142
      Location:432 → 1018
      PLN03142; Probable chromatin-remodeling complex ATPase chain; Provisional
      cd18661
      Location:340 → 411
      CD2_tandem_CHD1-2_like; repeat 2 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 1 and 2, and similar proteins
      cd18666
      Location:223 → 307
      CD1_tandem_CHD1-2_like; repeat 1 of the paired tandem chromodomains of chromodomain helicase DNA-binding protein 1 and 2, and similar proteins
      cd18054
      Location:428 → 664
      DEXHc_CHD2; DEAH-box helicase domain of the chromodomain helicase DNA binding protein 2
      pfam13907
      Location:1435 → 1517
      DUF4208; Domain of unknown function (DUF4208)
      pfam18375
      Location:1094 → 1182
      CDH1_2_SANT_HL1; CDH1/2 SANT-Helical linker 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037348.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      14043709..14155872 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059879128.1 → XP_059735111.1  chromodomain-helicase-DNA-binding protein 2 isoform X5

      UniProtKB/TrEMBL
      G3MXX3

    2. XM_059879125.1 → XP_059735108.1  chromodomain-helicase-DNA-binding protein 2 isoform X2

      UniProtKB/TrEMBL
      G3MXX3

    3. XM_059879123.1 → XP_059735106.1  chromodomain-helicase-DNA-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      G3MXX3

    4. XM_059879124.1 → XP_059735107.1  chromodomain-helicase-DNA-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      G3MXX3

    5. XM_059879129.1 → XP_059735112.1  chromodomain-helicase-DNA-binding protein 2 isoform X6

      UniProtKB/TrEMBL
      G3MXX3

    6. XM_059879126.1 → XP_059735109.1  chromodomain-helicase-DNA-binding protein 2 isoform X3

      UniProtKB/TrEMBL
      G3MXX3

    7. XM_059879127.1 → XP_059735110.1  chromodomain-helicase-DNA-binding protein 2 isoform X4

      UniProtKB/TrEMBL
      G3MXX3
    Nucleotide Protein Strain
    Heading Accession and Version

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