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    SIGIRR single Ig and TIR domain containing [ Bos taurus (domestic cattle) ]

    Gene ID: 531801, updated on 29-Jan-2025

    Summary

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    Official Symbol
    SIGIRRprovided by VGNC
    Official Full Name
    single Ig and TIR domain containingprovided by VGNC
    Primary source
    VGNC:VGNC:34616
    See related
    BGD:BT11722; Ensembl:ENSBTAG00000011149
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SIGIRR in Genome Data Viewer
    Location:
    chromosome: 29
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 29 NC_037356.1 (50869491..50877584)

    Chromosome 29 - NC_037356.1Genomic Context describing neighboring genes Neighboring gene phosphatidylserine synthase 2 Neighboring gene anoctamin 9 Neighboring gene plakophilin 3 Neighboring gene beta-1,4-N-acetyl-galactosaminyltransferase 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. TIR8 receptor expression in bovine tissues. Riva F, et al. Vet Immunol Immunopathol, 2010 Jul. PMID 20227770
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC140394

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    single Ig IL-1-related receptor
    Names
    single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082443.2 → NP_001075912.1  single Ig IL-1-related receptor

      See identical proteins and their annotated locations for NP_001075912.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133493
      UniProtKB/TrEMBL
      A0A3Q1ND60, A2VDZ6
      Conserved Domains (3) summary
      cd00096
      Location:28 → 106
      Ig; Immunoglobulin domain
      pfam07679
      Location:9 → 110
      I-set; Immunoglobulin I-set domain
      pfam01582
      Location:165 → 311
      TIR; TIR domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037356.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      50869491..50877584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005227365.5 → XP_005227422.1  single Ig IL-1-related receptor isoform X3

      See identical proteins and their annotated locations for XP_005227422.1

      UniProtKB/TrEMBL
      A0A3Q1ND60, A2VDZ6
      Related
      ENSBTAP00070041905.1, ENSBTAT00070068597.1
      Conserved Domains (3) summary
      cd00096
      Location:28 → 106
      Ig; Immunoglobulin domain
      pfam07679
      Location:9 → 110
      I-set; Immunoglobulin I-set domain
      pfam01582
      Location:165 → 311
      TIR; TIR domain

    2. XM_010821251.4 → XP_010819553.1  single Ig IL-1-related receptor isoform X1

      UniProtKB/TrEMBL
      G5E5E8
      Conserved Domains (3) summary
      cd00096
      Location:97 → 163
      Ig; Immunoglobulin domain
      pfam07679
      Location:78 → 167
      I-set; Immunoglobulin I-set domain
      pfam01582
      Location:222 → 368
      TIR; TIR domain

    3. XM_010821253.4 → XP_010819555.1  single Ig IL-1-related receptor isoform X2

      See identical proteins and their annotated locations for XP_010819555.1

      UniProtKB/TrEMBL
      A0A3Q1ND60
      Related
      ENSBTAP00070041885.1, ENSBTAT00070068560.1
      Conserved Domains (3) summary
      cd00096
      Location:70 → 148
      Ig; Immunoglobulin domain
      pfam07679
      Location:51 → 152
      I-set; Immunoglobulin I-set domain
      pfam01582
      Location:207 → 353
      TIR; TIR domain
    Nucleotide Protein Strain
    Heading Accession and Version

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