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    SFPQ splicing factor proline and glutamine rich [ Bos taurus (domestic cattle) ]

    Gene ID: 618226, updated on 1-Jan-2025

    Summary

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    Official Symbol
    SFPQprovided by VGNC
    Official Full Name
    splicing factor proline and glutamine richprovided by VGNC
    Primary source
    VGNC:VGNC:34518
    See related
    BGD:BT11385; Ensembl:ENSBTAG00000016328
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SFPQ in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (110557926..110573859)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene zinc finger MYM-type containing 4 Neighboring gene uncharacterized LOC112446145 Neighboring gene large ribosomal subunit protein eL6-like Neighboring gene zinc finger MYM-type containing 1 Neighboring gene small ribosomal subunit protein eS12-like Neighboring gene zinc finger MYM-type containing 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in alternative mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor, proline- and glutamine-rich
    Names
    splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206291.2 → NP_001193220.1  splicing factor, proline- and glutamine-rich

      See identical proteins and their annotated locations for NP_001193220.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000003
      UniProtKB/TrEMBL
      E1BQ37
      Related
      ENSBTAP00000021719.6, ENSBTAT00000021719.7
      Conserved Domains (4) summary
      cd12948
      Location:442 → 538
      NOPS_PSF; NOPS domain, including C-terminal coiled-coil region, in polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF) and similar proteins
      cd12333
      Location:372 → 451
      RRM2_p54nrb_like; RNA recognition motif 2 in the p54nrb/PSF/PSP1 family
      cd12587
      Location:296 → 366
      RRM1_PSF; RNA recognition motif 1 in vertebrate polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF)
      cl25742
      Location:497 → 595
      ERM; Ezrin/radixin/moesin family

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      110557926..110573859
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010803715.4 → XP_010802017.1  splicing factor, proline- and glutamine-rich isoform X1

      See identical proteins and their annotated locations for XP_010802017.1

      UniProtKB/TrEMBL
      E1BQ37
      Conserved Domains (4) summary
      cd12948
      Location:442 → 538
      NOPS_PSF; NOPS domain, including C-terminal coiled-coil region, in polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF) and similar proteins
      cd12333
      Location:372 → 451
      RRM2_p54nrb_like; RNA recognition motif 2 in the p54nrb/PSF/PSP1 family
      cd12587
      Location:296 → 366
      RRM1_PSF; RNA recognition motif 1 in vertebrate polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF)
      cl25742
      Location:497 → 595
      ERM; Ezrin/radixin/moesin family

    2. XM_005204862.5 → XP_005204919.1  splicing factor, proline- and glutamine-rich isoform X1

      See identical proteins and their annotated locations for XP_005204919.1

      UniProtKB/TrEMBL
      E1BQ37
      Conserved Domains (4) summary
      cd12948
      Location:442 → 538
      NOPS_PSF; NOPS domain, including C-terminal coiled-coil region, in polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF) and similar proteins
      cd12333
      Location:372 → 451
      RRM2_p54nrb_like; RNA recognition motif 2 in the p54nrb/PSF/PSP1 family
      cd12587
      Location:296 → 366
      RRM1_PSF; RNA recognition motif 1 in vertebrate polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF)
      cl25742
      Location:497 → 595
      ERM; Ezrin/radixin/moesin family

    3. XM_005204863.5 → XP_005204920.1  splicing factor, proline- and glutamine-rich isoform X2

      See identical proteins and their annotated locations for XP_005204920.1

      UniProtKB/TrEMBL
      A0A3Q1LXA1, A0AAA9SEK3
      Related
      ENSBTAP00000060140.1, ENSBTAT00000080233.2
      Conserved Domains (4) summary
      cd12948
      Location:442 → 538
      NOPS_PSF; NOPS domain, including C-terminal coiled-coil region, in polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF) and similar proteins
      cd12333
      Location:372 → 451
      RRM2_p54nrb_like; RNA recognition motif 2 in the p54nrb/PSF/PSP1 family
      cd12587
      Location:296 → 366
      RRM1_PSF; RNA recognition motif 1 in vertebrate polypyrimidine tract-binding protein (PTB)-associated-splicing factor (PSF)
      cl26511
      Location:499 → 599
      Neuromodulin_N; Gap junction protein N-terminal region
    Nucleotide Protein Strain
    Heading Accession and Version

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