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    ADCY2 adenylate cyclase 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 510708, updated on 1-Jan-2025

    Summary

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    Official Symbol
    ADCY2provided by VGNC
    Official Full Name
    adenylate cyclase 2provided by VGNC
    Primary source
    VGNC:VGNC:25643
    See related
    BGD:BT24683; Ensembl:ENSBTAG00000019210
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ADCY2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 20 NC_037347.1 (65388703..65843081, complement)

    Chromosome 20 - NC_037347.1Genomic Context describing neighboring genes Neighboring gene FAST kinase domains 3 Neighboring gene cilia and flagella associated protein 90 Neighboring gene uncharacterized LOC132343253 Neighboring gene uncharacterized LOC112443014 Neighboring gene transfer RNA cysteine (anticodon ACA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037347.1 Chromosome 20 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, sequence identification, and gene expression analysis of bovine ADCY2 gene. Li YX, et al. Mol Biol Rep, 2014 Jun. PMID 24797538
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These data will serve as a foundation for further insight into the cattle ADCY2 gene.
      Title: Molecular cloning, sequence identification, and gene expression analysis of bovine ADCY2 gene.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables adenylate cyclase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cAMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylate cyclase type 2
    XP_024837306.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037347.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      65388703..65843081 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024981538.2 → XP_024837306.1  adenylate cyclase type 2

      UniProtKB/TrEMBL
      A0AAA9SPU9, A0AAA9TFX0
      Related
      ENSBTAP00000095747.1, ENSBTAT00000129107.1
      Conserved Domains (3) summary
      pfam00211
      Location:878 → 1077
      Guanylate_cyc; Adenylate and Guanylate cyclase catalytic domain
      pfam06327
      Location:495 → 599
      DUF1053; Domain of Unknown Function (DUF1053)
      pfam16214
      Location:33 → 260
      AC_N; Adenylyl cyclase N-terminal extracellular and transmembrane region
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases
    Research Materials