EIF2B3 eukaryotic translation initiation factor 2B subunit gamma [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: EIF2B3provided by VGNC
Official Full Name: eukaryotic translation initiation factor 2B subunit gammaprovided by VGNC
Primary source: VGNC:VGNC:28386
See related: BGD:BT13051; Ensembl:ENSBTAG00000019010
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	3	NC_037330.1 (101059252..101173087)

Chromosome 3 - NC_037330.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cytoplasmic translational initiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of eukaryotic translation initiation factor 2B complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of guanyl-nucleotide exchange factor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: translation initiation factor eIF2B subunit gamma

Names: eIF-2B GDP-GTP exchange factor subunit gamma; eIF2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; translation initiation factor eIF-2B subunit gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001083474.1 → NP_001076943.1 translation initiation factor eIF2B subunit gamma

See identical proteins and their annotated locations for NP_001076943.1

Status: PROVISIONAL

Source sequence(s)

BC123704

UniProtKB/TrEMBL

A0AAA9THE2, A4FV40, E1BB97

Related

ENSBTAP00000093516.1, ENSBTAT00000116593.1

Conserved Domains (3) summary

cd04652
Location:358 → 438

LbH_eIF2B_gamma_C; eIF-2B gamma subunit, C-terminal Left-handed parallel beta-Helix (LbH) domain: eIF-2B is a eukaryotic translation initiator, a guanine nucleotide exchange factor (GEF) composed of five different subunits (alpha, beta, gamma, delta and epsilon). eIF2B is ...

cd04198
Location:3 → 213

eIF-2B_gamma_N; The N-terminal domain of gamma subunit of the eIF-2B is a subfamily of glycosyltransferase 2

COG1208
Location:4 → 447

GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]