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    ASPM assembly factor for spindle microtubules [ Bos taurus (domestic cattle) ]

    Gene ID: 534849, updated on 1-Jan-2025

    Summary

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    Official Symbol
    ASPMprovided by VGNC
    Official Full Name
    assembly factor for spindle microtubulesprovided by VGNC
    Primary source
    VGNC:VGNC:109384
    See related
    BGD:BT24241; Ensembl:ENSBTAG00000007860
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ASPM in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (76021939..76082066, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene coagulation factor XIII B chain Neighboring gene complement factor H related 5 Neighboring gene zinc finger and BTB domain containing 41 Neighboring gene crumbs cell polarity complex component 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Evolution of the human ASPM gene, a major determinant of brain size. Zhang J. Genetics, 2003 Dec. PMID 14704186, Free PMC Article
    2. Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans. Evans PD, et al. Hum Mol Genet, 2004 Mar 1. PMID 14722158
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in establishment of meiotic spindle localization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in spindle organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    abnormal spindle-like microcephaly-associated protein homolog
    Names
    abnormal spindle microtubule assembly
    asp (abnormal spindle) homolog, microcephaly associated
    asp (abnormal spindle)-like, microcephaly associated

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206506.2 → NP_001193435.2  abnormal spindle-like microcephaly-associated protein homolog

      Status: VALIDATED

      Source sequence(s)
      NKLS02000016
      Related
      ENSBTAP00000010340.6, ENSBTAT00000010340.7

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      76021939..76082066 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P62285.1 GenPept UniProtKB/Swiss-Prot:P62285

    Gene LinkOut

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