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    WDR19 WD repeat domain 19 [ Bos taurus (domestic cattle) ]

    Gene ID: 533633, updated on 27-Dec-2024

    Summary

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    Official Symbol
    WDR19provided by VGNC
    Official Full Name
    WD repeat domain 19provided by VGNC
    Primary source
    VGNC:VGNC:36886
    See related
    BGD:BT22166; Ensembl:ENSBTAG00000014512
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See WDR19 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (58350006..58428624)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 156 Neighboring gene kelch like family member 5 Neighboring gene replication factor C subunit 1 Neighboring gene transfer RNA histidin (anticodon GUG) Neighboring gene klotho beta

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility. Hiltpold M, et al. PLoS Genet, 2020 May. PMID 32407316, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intraciliary retrograde transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of intraciliary transport particle A IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    WD repeat-containing protein 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206027.3 → NP_001192956.3  WD repeat-containing protein 19

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000006
      UniProtKB/TrEMBL
      A0AAA9SHW9, E1B7Q4
      Related
      ENSBTAP00000019294.6, ENSBTAT00000019294.6
      Conserved Domains (6) summary
      COG0457
      Location:748 → 937
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      COG2319
      Location:19 → 345
      WD40; WD40 repeat [General function prediction only]
      sd00006
      Location:779 → 803
      TPR; TPR repeat [structural motif]
      sd00039
      Location:100 → 137
      7WD40; WD40 repeat [structural motif]
      pfam15911
      Location:508 → 564
      WD40_3; WD domain, G-beta repeat
      cl26078
      Location:851 → 964
      Clathrin; Region in Clathrin and VPS

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      58350006..58428624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015471584.3 → XP_015327070.2  WD repeat-containing protein 19 isoform X3

      UniProtKB/TrEMBL
      A0AAA9SHW9
      Conserved Domains (6) summary
      COG0457
      Location:748 → 937
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      COG2319
      Location:19 → 345
      WD40; WD40 repeat [General function prediction only]
      sd00006
      Location:779 → 803
      TPR; TPR repeat [structural motif]
      sd00039
      Location:100 → 137
      7WD40; WD40 repeat [structural motif]
      pfam15911
      Location:508 → 564
      WD40_3; WD domain, G-beta repeat
      cl26078
      Location:851 → 964
      Clathrin; Region in Clathrin and VPS

    2. XM_015471581.3 → XP_015327067.2  WD repeat-containing protein 19 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MXD0, A0AAA9SHW9
      Related
      ENSBTAP00000060351.2, ENSBTAT00000069073.2
      Conserved Domains (6) summary
      COG0457
      Location:707 → 896
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      COG2319
      Location:19 → 345
      WD40; WD40 repeat [General function prediction only]
      sd00006
      Location:738 → 762
      TPR; TPR repeat [structural motif]
      sd00039
      Location:100 → 137
      7WD40; WD40 repeat [structural motif]
      pfam15911
      Location:467 → 523
      WD40_3; WD domain, G-beta repeat
      cl26078
      Location:810 → 923
      Clathrin; Region in Clathrin and VPS

    3. XM_015471582.3 → XP_015327068.2  WD repeat-containing protein 19 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SHW9
      Conserved Domains (6) summary
      COG0457
      Location:689 → 878
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      COG2319
      Location:1 → 286
      WD40; WD40 repeat [General function prediction only]
      sd00006
      Location:720 → 744
      TPR; TPR repeat [structural motif]
      sd00039
      Location:41 → 78
      7WD40; WD40 repeat [structural motif]
      pfam15911
      Location:449 → 505
      WD40_3; WD domain, G-beta repeat
      cl26078
      Location:792 → 905
      Clathrin; Region in Clathrin and VPS

    RNA

    1. XR_009494782.1 RNA Sequence

    2. XR_009494783.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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