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    STRADA STE20 related adaptor alpha [ Bos taurus (domestic cattle) ]

    Gene ID: 515024, updated on 30-Jan-2025

    Summary

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    Official Symbol
    STRADAprovided by VGNC
    Official Full Name
    STE20 related adaptor alphaprovided by VGNC
    Primary source
    VGNC:VGNC:35418
    See related
    BGD:BT23908; EnsemblRapid:ENSBTAG00070021069
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    LYK5
    Orthologs
    human mouse all
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    Genomic context

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    See STRADA in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (47980018..48012780, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 3 Neighboring gene basic proline-rich protein-like Neighboring gene LIM domain containing 2 Neighboring gene coiled-coil domain containing 47 Neighboring gene DEAD-box helicase 42 Neighboring gene FtsJ RNA 2'-O-methyltransferase 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein export from nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of serine/threonine protein kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    STE20-related kinase adapter protein alpha
    Names
    STE20-related adapter protein
    STE20-related kinase adaptor alpha
    STRAD alpha
    protein kinase LYK5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015603.1 → NP_001015603.1  STE20-related kinase adapter protein alpha

      See identical proteins and their annotated locations for NP_001015603.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020921
      UniProtKB/Swiss-Prot
      Q5E9J9
      UniProtKB/TrEMBL
      A0AAF6YFZ5
      Conserved Domains (1) summary
      cd08227
      Location:12 → 338
      PK_STRAD_alpha; Pseudokinase domain of STE20-related kinase adapter protein alpha

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      47980018..48012780 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059878008.1 → XP_059733991.1  STE20-related kinase adapter protein alpha isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MX20, F6QWI1

    2. XM_059878007.1 → XP_059733990.1  STE20-related kinase adapter protein alpha isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MX20, F6QWI1

    3. XM_059878013.1 → XP_059733996.1  STE20-related kinase adapter protein alpha isoform X3

      UniProtKB/TrEMBL
      A0AAA9SWM7, A0AAF6YFZ5

    4. XM_059878020.1 → XP_059734003.1  STE20-related kinase adapter protein alpha isoform X6

      UniProtKB/Swiss-Prot
      Q5E9J9
      UniProtKB/TrEMBL
      A0AAF6YFZ5

    5. XM_005220868.5 → XP_005220925.1  STE20-related kinase adapter protein alpha isoform X5

      See identical proteins and their annotated locations for XP_005220925.1

      UniProtKB/TrEMBL
      A0AAF6YFZ5, A2VE62
      Conserved Domains (1) summary
      cd08227
      Location:33 → 359
      PK_STRAD_alpha; Pseudokinase domain of STE20-related kinase adapter protein alpha

    6. XM_059878009.1 → XP_059733992.1  STE20-related kinase adapter protein alpha isoform X2

      UniProtKB/TrEMBL
      F6QWI1

    7. XM_005220865.5 → XP_005220922.1  STE20-related kinase adapter protein alpha isoform X3

      See identical proteins and their annotated locations for XP_005220922.1

      UniProtKB/TrEMBL
      A0AAA9SWM7, A0AAF6YFZ5
      Related
      ENSBTAP00070028569.1, ENSBTAT00070047742.1
      Conserved Domains (1) summary
      cd08227
      Location:41 → 367
      PK_STRAD_alpha; Pseudokinase domain of STE20-related kinase adapter protein alpha

    8. XM_010816345.4 → XP_010814647.2  STE20-related kinase adapter protein alpha isoform X7

      Conserved Domains (1) summary
      cl21453
      Location:70 → 194
      PKc_like; Protein Kinases, catalytic domain

    9. XM_059878004.1 → XP_059733987.1  STE20-related kinase adapter protein alpha isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MX20, F6QWI1
      Related
      ENSBTAP00070028585.1, ENSBTAT00070047774.1

    10. XM_059878017.1 → XP_059734000.1  STE20-related kinase adapter protein alpha isoform X5

      UniProtKB/TrEMBL
      A0AAF6YFZ5, A2VE62

    11. XM_059878011.1 → XP_059733994.1  STE20-related kinase adapter protein alpha isoform X2

      UniProtKB/TrEMBL
      F6QWI1

    12. XM_059878006.1 → XP_059733989.1  STE20-related kinase adapter protein alpha isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MX20, F6QWI1

    13. XM_059878005.1 → XP_059733988.1  STE20-related kinase adapter protein alpha isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MX20, F6QWI1
      Related
      ENSBTAP00070028561.1, ENSBTAT00070047728.1

    14. XM_059878021.1 → XP_059734004.1  STE20-related kinase adapter protein alpha isoform X6

      UniProtKB/Swiss-Prot
      Q5E9J9
      UniProtKB/TrEMBL
      A0AAF6YFZ5

    15. XM_059878016.1 → XP_059733999.1  STE20-related kinase adapter protein alpha isoform X5

      UniProtKB/TrEMBL
      A0AAF6YFZ5, A2VE62

    16. XM_059878010.1 → XP_059733993.1  STE20-related kinase adapter protein alpha isoform X2

      UniProtKB/TrEMBL
      F6QWI1

    17. XM_059878019.1 → XP_059734002.1  STE20-related kinase adapter protein alpha isoform X6

      UniProtKB/Swiss-Prot
      Q5E9J9
      UniProtKB/TrEMBL
      A0AAF6YFZ5

    18. XM_059878018.1 → XP_059734001.1  STE20-related kinase adapter protein alpha isoform X6

      UniProtKB/Swiss-Prot
      Q5E9J9
      UniProtKB/TrEMBL
      A0AAF6YFZ5

    19. XM_059878015.1 → XP_059733998.1  STE20-related kinase adapter protein alpha isoform X4

      UniProtKB/TrEMBL
      A0AAA9RZX2, A0AAF6YFZ5
      Related
      ENSBTAP00070028449.1, ENSBTAT00070047555.1

    20. XM_059878014.1 → XP_059733997.1  STE20-related kinase adapter protein alpha isoform X4

      UniProtKB/TrEMBL
      A0AAA9RZX2, A0AAF6YFZ5

    21. XM_059878023.1 → XP_059734006.1  STE20-related kinase adapter protein alpha isoform X9

      UniProtKB/TrEMBL
      A0AAA9S8Y1
      Related
      ENSBTAP00070028551.1, ENSBTAT00070047708.1

    22. XM_059878022.1 → XP_059734005.1  STE20-related kinase adapter protein alpha isoform X8

      UniProtKB/TrEMBL
      A0AAF7A9L2
      Related
      ENSBTAP00070028559.1, ENSBTAT00070047722.1
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E9J9.1 GenPept UniProtKB/Swiss-Prot:Q5E9J9

    Gene LinkOut

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