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    CMTR1 cap methyltransferase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 509620, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CMTR1provided by VGNC
    Official Full Name
    cap methyltransferase 1provided by VGNC
    Primary source
    VGNC:VGNC:27489
    See related
    BGD:BT21414; Ensembl:ENSBTAG00000017091
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    MTr1; FTSJD2
    Orthologs
    human mouse all
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    Genomic context

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    See CMTR1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (11318812..11371568)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 8 Neighboring gene elongation factor 1-alpha 1-like Neighboring gene coiled-coil domain containing 167 Neighboring gene MAM domain containing glycosylphosphatidylinositol anchor 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC148378

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA (nucleoside-2'-O-)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 7-methylguanosine mRNA capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
    Names
    FtsJ methyltransferase domain containing 2
    cap1 2'O-ribose methyltransferase 1
    ftsJ methyltransferase domain-containing protein 2
    NP_001075899.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082430.2 → NP_001075899.1  cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1

      See identical proteins and their annotated locations for NP_001075899.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133559
      UniProtKB/Swiss-Prot
      A2VE39
      UniProtKB/TrEMBL
      A0AAA9T3C5
      Related
      ENSBTAP00000022726.6, ENSBTAT00000022726.7
      Conserved Domains (4) summary
      smart00456
      Location:753 → 786
      WW; Domain with 2 conserved Trp (W) residues
      pfam01585
      Location:87 → 129
      G-patch; G-patch domain
      pfam01728
      Location:232 → 448
      FtsJ; FtsJ-like methyltransferase
      cl12015
      Location:623 → 716
      Adenylation_DNA_ligase_like; Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      11318812..11371568
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2VE39.1 GenPept UniProtKB/Swiss-Prot:A2VE39

    Gene LinkOut

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