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    CRBN cereblon [ Bos taurus (domestic cattle) ]

    Gene ID: 511585, updated on 27-Dec-2024

    Summary

    Official Symbol
    CRBNprovided by VGNC
    Official Full Name
    cereblonprovided by VGNC
    Primary source
    VGNC:VGNC:27690
    See related
    BGD:BT30183; Ensembl:ENSBTAG00000019536
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See CRBN in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 22 NC_037349.1 (23125513..23147297)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112443450 Neighboring gene uncharacterized LOC112443448 Neighboring gene uncharacterized LOC112443451 Neighboring gene tRNA nucleotidyl transferase 1 Neighboring gene interleukin 5 receptor subunit alpha

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037349.1 Chromosome 22 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075527.1NP_001068995.1  protein cereblon

      See identical proteins and their annotated locations for NP_001068995.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120452
      UniProtKB/Swiss-Prot
      Q0P564
      Related
      ENSBTAP00000026031.5, ENSBTAT00000026031.7
      Conserved Domains (3) summary
      cl19481
      Location:81188
      LON; Found in ATP-dependent protease La (LON)
      cd15777
      Location:323424
      CRBN_C_like; Thalidomide-binding C-terminal domain of cereblon (CRBN) and similar protein domains
      pfam02190
      Location:82319
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23125513..23147297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)