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    LIPC lipase C, hepatic type [ Bos taurus (domestic cattle) ]

    Gene ID: 535192, updated on 29-Jan-2025

    Summary

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    Official Symbol
    LIPCprovided by VGNC
    Official Full Name
    lipase C, hepatic typeprovided by VGNC
    Primary source
    VGNC:VGNC:58357
    See related
    Ensembl:ENSBTAG00000005479
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LIPC in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (51696929..51859042, complement)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene iron-sulfur cluster scaffold homolog (E. coli)-like Neighboring gene ADAM metallopeptidase domain 10 Neighboring gene uncharacterized LOC101903685 Neighboring gene uncharacterized LOC112448468 Neighboring gene uncharacterized LOC112448583 Neighboring gene methylosome subunit pICln-like Neighboring gene uncharacterized LOC112448657 Neighboring gene aquaporin 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128376

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables apolipoprotein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipoprotein lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in triglyceride catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hepatic triacylglycerol lipase
    Names
    HL
    hepatic lipase
    lipase member C
    lipase, hepatic
    lysophospholipase
    phospholipase A1
    NP_001030487.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001035410.2 → NP_001030487.1  hepatic triacylglycerol lipase precursor

      See identical proteins and their annotated locations for NP_001030487.1

      Status: PROVISIONAL

      Source sequence(s)
      BC103072
      UniProtKB/Swiss-Prot
      Q3SZ79
      UniProtKB/TrEMBL
      A0AAA9TSL1
      Related
      ENSBTAP00070044819.1, ENSBTAT00070073550.1
      Conserved Domains (2) summary
      cd01758
      Location:353 → 488
      PLAT_LPL; PLAT/ LH2 domain present in lipoprotein lipase (LPL). LPL is a key enzyme in catabolism of plasma lipoprotein triglycerides (TGs) and has therefeore has a profound influence on triglyceride and high-density lipoprotein (HDL) cholesterol levels in the ...
      pfam00151
      Location:23 → 350
      Lipase; Lipase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      51696929..51859042 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SZ79.1 GenPept UniProtKB/Swiss-Prot:Q3SZ79

    Gene LinkOut

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