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    EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 533087, updated on 29-Jan-2025

    Summary

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    Official Symbol
    EZH1provided by VGNC
    Official Full Name
    enhancer of zeste 1 polycomb repressive complex 2 subunitprovided by VGNC
    Primary source
    VGNC:VGNC:28674
    See related
    BGD:BT16751; Ensembl:ENSBTAG00000021918
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See EZH1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (42754605..42786906, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology, MyTH4 and FERM domain containing H3 Neighboring gene contactin associated protein 1 Neighboring gene C-C motif chemokine receptor 10 Neighboring gene receptor activity modifying protein 2 Neighboring gene vacuolar protein sorting 25 homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC157156

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone H3K27 methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heterochromatin formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ESC/E(Z) complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone-lysine N-methyltransferase EZH1
    Names
    enhancer of zeste homolog 1
    NP_001421973.1
    NP_001421974.1
    NP_001421975.1
    XP_059734098.1
    XP_059734099.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001435044.1 → NP_001421973.1  histone-lysine N-methyltransferase EZH1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000019
      Related
      ENSBTAP00070034771.1, ENSBTAT00070058443.1

    2. NM_001435045.1 → NP_001421974.1  histone-lysine N-methyltransferase EZH1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000019

    3. NM_001435046.1 → NP_001421975.1  histone-lysine N-methyltransferase EZH1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000019

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      42754605..42786906 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059878116.1 → XP_059734099.1  histone-lysine N-methyltransferase EZH1 isoform X1

      UniProtKB/Swiss-Prot
      A7E2Z2
      UniProtKB/TrEMBL
      A0AAA9SGT4

    2. XM_059878115.1 → XP_059734098.1  histone-lysine N-methyltransferase EZH1 isoform X1

      UniProtKB/Swiss-Prot
      A7E2Z2
      UniProtKB/TrEMBL
      A0AAA9SGT4

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001102151.2: Suppressed sequence

      Description
      NM_001102151.2: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A7E2Z2.2 GenPept UniProtKB/Swiss-Prot:A7E2Z2

    Gene LinkOut

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