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    SHLD1 shieldin complex subunit 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 615129, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SHLD1provided by VGNC
    Official Full Name
    shieldin complex subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:49170
    See related
    BGD:BT19154; Ensembl:ENSBTAG00000014048
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    C20orf196; C13H20orf196
    Orthologs
    human mouse all
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    Genomic context

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    See SHLD1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 13 NC_037340.1 (47916941..48032657)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene mitochondrial inner membrane protease subunit 1-like Neighboring gene uncharacterized LOC132346917 Neighboring gene chromogranin B Neighboring gene tRNA methyltransferase 6 non-catalytic subunit Neighboring gene minichromosome maintenance 8 homologous recombination repair factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037340.1 Chromosome 13 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. An OB-fold complex controls the repair pathways for DNA double-strand breaks. Gao S, et al. Nat Commun, 2018 Sep 25. PMID 30254264, Free PMC Article
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. An OB-fold complex controls the repair pathways for DNA double-strand breaks.
      Title: An OB-fold complex controls the repair pathways for DNA double-strand breaks.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Clone Names

    • MGC137607

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in negative regulation of double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of double-strand break repair via nonhomologous end joining IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of isotype switching IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in site of double-strand break IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    shieldin complex subunit 1
    Names
    RINN1-REV7-interacting novel NHEJ regulator 3
    chromosome 13 C20orf196 homolog
    uncharacterized protein C20orf196 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046552.2 → NP_001040017.1  shieldin complex subunit 1

      See identical proteins and their annotated locations for NP_001040017.1

      Status: PROVISIONAL

      Source sequence(s)
      BC112619
      UniProtKB/Swiss-Prot
      Q2KIJ1
      UniProtKB/TrEMBL
      A0AAF7A7J7
      Related
      ENSBTAP00000039142.3, ENSBTAT00000039347.4
      Conserved Domains (1) summary
      pfam15021
      Location:3 → 202
      DUF4521; Protein of unknown function (DUF4521)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      47916941..48032657
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015474183.3 → XP_015329669.1  shieldin complex subunit 1 isoform X5

      Conserved Domains (1) summary
      pfam15021
      Location:3 → 59
      DUF4521; Protein of unknown function (DUF4521)

    2. XM_005214847.5 → XP_005214904.1  shieldin complex subunit 1 isoform X1

      See identical proteins and their annotated locations for XP_005214904.1

      UniProtKB/Swiss-Prot
      Q2KIJ1
      UniProtKB/TrEMBL
      A0AAF7A7J7
      Conserved Domains (1) summary
      pfam15021
      Location:3 → 202
      DUF4521; Protein of unknown function (DUF4521)

    3. XM_025000811.2 → XP_024856579.1  shieldin complex subunit 1 isoform X3

      Conserved Domains (1) summary
      pfam15021
      Location:3 → 59
      DUF4521; Protein of unknown function (DUF4521)

    4. XM_025000812.2 → XP_024856580.1  shieldin complex subunit 1 isoform X4

      Conserved Domains (1) summary
      pfam15021
      Location:3 → 68
      DUF4521; Protein of unknown function (DUF4521)

    5. XM_059892761.1 → XP_059748744.1  shieldin complex subunit 1 isoform X2

    6. XM_025000814.2 → XP_024856582.1  shieldin complex subunit 1 isoform X5

      Conserved Domains (1) summary
      pfam15021
      Location:3 → 59
      DUF4521; Protein of unknown function (DUF4521)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2KIJ1.1 GenPept UniProtKB/Swiss-Prot:Q2KIJ1

    Gene LinkOut

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