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    SLC25A25 solute carrier family 25 member 25 [ Bos taurus (domestic cattle) ]

    Gene ID: 527786, updated on 1-Jan-2025

    Summary

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    Official Symbol
    SLC25A25provided by VGNC
    Official Full Name
    solute carrier family 25 member 25provided by VGNC
    Primary source
    VGNC:VGNC:34751
    See related
    BGD:BT19419; Ensembl:ENSBTAG00000011912
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SLC25A25 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (98708672..98748919)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132346636 Neighboring gene estrogen-induced osteoclastogenesis regulator 1 Neighboring gene nuclear apoptosis inducing factor 1 Neighboring gene prostaglandin E synthase 2 Neighboring gene lipocalin 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC127973

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in ADP transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ATP transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcium-binding mitochondrial carrier protein SCaMC-2
    Names
    small calcium-binding mitochondrial carrier protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038145.2 → NP_001033234.1  calcium-binding mitochondrial carrier protein SCaMC-2

      See identical proteins and their annotated locations for NP_001033234.1

      Status: PROVISIONAL

      Source sequence(s)
      BC108098
      UniProtKB/Swiss-Prot
      Q0V7M4
      Related
      ENSBTAP00000015802.6, ENSBTAT00000015802.6
      Conserved Domains (4) summary
      cd00051
      Location:82 → 141
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00153
      Location:186 → 274
      Mito_carr; Mitochondrial carrier protein
      pfam13499
      Location:83 → 138
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:29 → 77
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      98708672..98748919
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891304.1 → XP_059747287.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X6

    2. XM_005213289.4 → XP_005213346.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X2

      UniProtKB/TrEMBL
      A0A452DJ52
      Related
      ENSBTAP00000032680.5, ENSBTAT00000032751.6
      Conserved Domains (2) summary
      PTZ00184
      Location:52 → 171
      PTZ00184; calmodulin; Provisional
      PTZ00169
      Location:223 → 477
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

    3. XM_005213288.5 → XP_005213345.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1

      Conserved Domains (5) summary
      cd15898
      Location:114 → 143
      EFh_PI-PLC; EF-hand motif [structural motif]
      cd15897
      Location:46 → 76
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:52 → 156
      EFh_PEF; The penta-EF hand (PEF) family
      cl28162
      Location:235 → 489
      Mito_carr; Mitochondrial carrier protein
      cl28895
      Location:114 → 203
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes

    4. XM_005213290.5 → XP_005213347.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LP89
      Related
      ENSBTAP00000061882.1, ENSBTAT00000072124.2
      Conserved Domains (4) summary
      cd00051
      Location:102 → 173
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00153
      Location:308 → 400
      Mito_carr; Mitochondrial carrier protein
      pfam13499
      Location:103 → 170
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:63 → 97
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    5. XM_005213291.5 → XP_005213348.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X4

      Conserved Domains (4) summary
      cd00051
      Location:102 → 161
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam00153
      Location:296 → 388
      Mito_carr; Mitochondrial carrier protein
      pfam13499
      Location:103 → 158
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:63 → 97
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    6. XM_005213292.5 → XP_005213349.1  calcium-binding mitochondrial carrier protein SCaMC-2 isoform X5

      UniProtKB/TrEMBL
      A0A452DIG9
      Conserved Domains (5) summary
      cd15898
      Location:82 → 111
      EFh_PI-PLC; EF-hand motif [structural motif]
      cd15897
      Location:53 → 77
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:53 → 125
      EFh_PEF; The penta-EF hand (PEF) family
      cl28162
      Location:203 → 457
      Mito_carr; Mitochondrial carrier protein
      cl28895
      Location:82 → 171
      EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0V7M4.1 GenPept UniProtKB/Swiss-Prot:Q0V7M4

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