EIF2A eukaryotic translation initiation factor 2A [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: EIF2Aprovided by VGNC
Official Full Name: eukaryotic translation initiation factor 2Aprovided by VGNC
Primary source: VGNC:VGNC:28379
See related: BGD:BT30266; Ensembl:ENSBTAG00000009106
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	1	NC_037328.1 (117556215..117597949, complement)

Chromosome 1 - NC_037328.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

DVEPC30 (e-PCR)
- UniSTS:253765

DVEPC097 (e-PCR)
- UniSTS:46201

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables mRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ribosome binding	IEA Inferred from Electronic Annotation more info	PubMed
enables tRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in translational initiation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cytosolic small ribosomal subunit	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: eukaryotic translation initiation factor 2A

Names: eukaryotic translation initiation factor 2A, 65kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001102283.1 → NP_001095753.1 eukaryotic translation initiation factor 2A

See identical proteins and their annotated locations for NP_001095753.1

Status: PROVISIONAL

Source sequence(s)

BC149970

UniProtKB/TrEMBL

A6QQS1, F1MBF0

Related

ENSBTAP00000012002.5, ENSBTAT00000012002.6

Conserved Domains (4) summary

pfam05308
Location:436 → 522

Mito_fiss_reg; Mitochondrial fission regulator

pfam08662
Location:216 → 411

eIF2A; Eukaryotic translation initiation factor eIF2A

sd00039
Location:277 → 311

7WD40; WD40 repeat [structural motif]

cl02567
Location:43 → 143

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...