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    PDLIM3 PDZ and LIM domain 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 538516, updated on 27-Dec-2024

    Summary

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    Official Symbol
    PDLIM3provided by VGNC
    Official Full Name
    PDZ and LIM domain 3provided by VGNC
    Primary source
    VGNC:VGNC:32709
    See related
    BGD:BT10971; Ensembl:ENSBTAG00000017183
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See PDLIM3 in Genome Data Viewer
    Location:
    chromosome: 27
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 27 NC_037354.1 (15712963..15743833, complement)

    Chromosome 27 - NC_037354.1Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 96 Neighboring gene coiled-coil domain containing 110 Neighboring gene sorbin and SH3 domain containing 2 Neighboring gene uncharacterized LOC112444648 Neighboring gene uncharacterized LOC132344049 Neighboring gene toll like receptor 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC128819

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables muscle alpha-actinin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in muscle structure development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Z disc IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of filamentous actin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in stress fiber IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PDZ and LIM domain protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034646.1 → NP_001029818.1  PDZ and LIM domain protein 3

      Status: PROVISIONAL

      Source sequence(s)
      BC103313
      UniProtKB/Swiss-Prot
      Q3SYZ8
      Related
      ENSBTAP00000022835.2, ENSBTAT00000022835.3
      Conserved Domains (3) summary
      cd09450
      Location:246 → 298
      LIM_ALP; This family represents the LIM domain of ALP, actinin-associated LIM protein
      cd00992
      Location:2 → 80
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:137 → 218
      DUF4749; Domain of unknown function (DUF4749)

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037354.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      15712963..15743833 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005226000.5 → XP_005226057.1  PDZ and LIM domain protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LYV9
      Related
      ENSBTAP00000062470.1, ENSBTAT00000075462.2
      Conserved Domains (3) summary
      cd09450
      Location:206 → 258
      LIM_ALP; This family represents the LIM domain of ALP, actinin-associated LIM protein
      cd00992
      Location:2 → 80
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:139 → 178
      DUF4749; Domain of unknown function (DUF4749)

    2. XM_005225999.5 → XP_005226056.1  PDZ and LIM domain protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1MQS4
      Related
      ENSBTAP00000074391.1, ENSBTAT00000074205.2
      Conserved Domains (3) summary
      cd09450
      Location:294 → 346
      LIM_ALP; This family represents the LIM domain of ALP, actinin-associated LIM protein
      cd00992
      Location:2 → 80
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam15936
      Location:184 → 266
      DUF4749; Domain of unknown function (DUF4749)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SYZ8.1 GenPept UniProtKB/Swiss-Prot:Q3SYZ8

    Gene LinkOut

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