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    POLR1D RNA polymerase I and III subunit D [ Bos taurus (domestic cattle) ]

    Gene ID: 539061, updated on 1-Jan-2025

    Summary

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    Gene symbol
    POLR1D
    Gene description
    RNA polymerase I and III subunit D
    See related
    BGD:BT22756; Ensembl:ENSBTAG00000008642
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See POLR1D in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (32288431..32321359, complement)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene GS homeobox 1 Neighboring gene ligand of numb-protein X 2 Neighboring gene mitochondrial translational initiation factor 3 Neighboring gene general transcription factor IIIA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC134497

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase I activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase III activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of RNA polymerase III complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA-directed RNA polymerases I and III subunit RPAC2
    Names
    DNA-directed RNA polymerase I subunit D
    RNA polymerase I subunit D
    RNA polymerases I and III subunit AC2
    polymerase (RNA) I polypeptide D, 16kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046587.2 → NP_001040052.1  DNA-directed RNA polymerases I and III subunit RPAC2 isoform 1

      See identical proteins and their annotated locations for NP_001040052.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the shorter isoform (1).
      Source sequence(s)
      DT857482, EH199872, EV743236, EV786928
      UniProtKB/TrEMBL
      A0AAA9U219, Q2YDK5

    2. NM_001076144.2 → NP_001069612.1  DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2

      See identical proteins and their annotated locations for NP_001069612.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the coding region and the 3' UTR compared to variant 1. The encoded isoform (2) is longer and has a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      BC114905, DT857457, DT857482, EH199872, EV786928
      UniProtKB/Swiss-Prot
      Q1RMG8
      Related
      ENSBTAP00000044471.3, ENSBTAT00000047251.5
      Conserved Domains (1) summary
      cd07029
      Location:30 → 114
      RNAP_I_III_AC19; AC19 subunit of Eukaryotic RNA polymerase (RNAP) I and RNAP III

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      32288431..32321359 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1RMG8.1 GenPept UniProtKB/Swiss-Prot:Q1RMG8

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