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    RNF34 ring finger protein 34 [ Bos taurus (domestic cattle) ]

    Gene ID: 506764, updated on 27-Dec-2024

    Summary

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    Official Symbol
    RNF34provided by VGNC
    Official Full Name
    ring finger protein 34provided by VGNC
    Primary source
    VGNC:VGNC:34063
    See related
    BGD:BT29336; Ensembl:ENSBTAG00000002315
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See RNF34 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 17 NC_037344.1 (53772945..53797168, complement)

    Chromosome 17 - NC_037344.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132342615 Neighboring gene lysine demethylase 2B Neighboring gene tetraspanin-33-like Neighboring gene anaphase promoting complex subunit 5 Neighboring gene calcium/calmodulin dependent protein kinase kinase 2 Neighboring gene transfer RNA arginine (anticodon CCU)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037344.1 Chromosome 17 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC134085

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein K48-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF34
    Names
    RING-type E3 ubiquitin transferase RNF34
    NP_001014858.1
    XP_005217821.1
    XP_024832862.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014858.1 → NP_001014858.1  E3 ubiquitin-protein ligase RNF34

      See identical proteins and their annotated locations for NP_001014858.1

      Status: PROVISIONAL

      Source sequence(s)
      BT020924
      UniProtKB/Swiss-Prot
      Q5E9J6
      UniProtKB/TrEMBL
      A0A3Q1ML57
      Related
      ENSBTAP00000072374.2, ENSBTAT00000083448.2
      Conserved Domains (2) summary
      cd15769
      Location:59 → 105
      FYVE_CARP1; FYVE-like domain found in caspase regulator CARP1 and similar proteins
      cd16706
      Location:327 → 365
      RING-HC_CARP1; RING finger, HC subclass, found in caspases-8 and -10-associated RING finger protein 1 (CARP1) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037344.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53772945..53797168 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005217764.3 → XP_005217821.1  E3 ubiquitin-protein ligase RNF34 isoform X1

      See identical proteins and their annotated locations for XP_005217821.1

      UniProtKB/TrEMBL
      A0A3Q1ML57, Q2YDF5
      Conserved Domains (2) summary
      cd15769
      Location:52 → 98
      FYVE_CARP1; FYVE-like domain found in caspase regulator CARP1 and similar proteins
      cd16706
      Location:320 → 358
      RING-HC_CARP1; RING finger, HC subclass, found in caspases-8 and -10-associated RING finger protein 1 (CARP1) and similar proteins

    2. XM_024977094.2 → XP_024832862.1  E3 ubiquitin-protein ligase RNF34 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1ML57, A0AAF6YJQ2
      Related
      ENSBTAP00000002986.3, ENSBTAT00000002986.4
      Conserved Domains (2) summary
      cd15769
      Location:59 → 105
      FYVE_CARP1; FYVE-like domain found in caspase regulator CARP1 and similar proteins
      cd16500
      Location:293 → 331
      RING-HC_CARP; RING finger, HC subclass, found in caspases-8 and -10-associated RING finger protein CARP-1, CARP-2 and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5E9J6.1 GenPept UniProtKB/Swiss-Prot:Q5E9J6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.