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    ASB3 ankyrin repeat and SOCS box containing 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 540802, updated on 1-Jan-2025

    Summary

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    Gene symbol
    ASB3
    Gene description
    ankyrin repeat and SOCS box containing 3
    See related
    BGD:BT18168; Ensembl:ENSBTAG00000019458
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    ASB-3
    Orthologs
    human mouse all
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    Genomic context

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    See ASB3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (36401340..36519701, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RNF185-like Neighboring gene probable D-tyrosyl-tRNA(Tyr) deacylase 2 pseudogene Neighboring gene BRCA1-associated RING domain protein 1-like Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 2 Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene G protein-coupled receptor 75

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC142427

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to ciliary inversin compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in ciliary inversin compartment IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ankyrin repeat and SOCS box protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076927.1 → NP_001070395.1  ankyrin repeat and SOCS box protein 3

      See identical proteins and their annotated locations for NP_001070395.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123548
      UniProtKB/Swiss-Prot
      Q08DV6
      Related
      ENSBTAP00000025921.5, ENSBTAT00000025921.6
      Conserved Domains (4) summary
      cd00204
      Location:146 → 267
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03722
      Location:458 → 508
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      pfam12796
      Location:83 → 176
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      36401340..36519701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891440.1 → XP_059747423.1  ankyrin repeat and SOCS box protein 3 isoform X2

    2. XM_059891441.1 → XP_059747424.1  ankyrin repeat and SOCS box protein 3 isoform X3

    3. XM_059891439.1 → XP_059747422.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      F1MN41

    4. XM_015473453.3 → XP_015328939.1  ankyrin repeat and SOCS box protein 3 isoform X1

      UniProtKB/TrEMBL
      F1MN41
      Conserved Domains (4) summary
      cd00204
      Location:146 → 267
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd03722
      Location:458 → 508
      SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
      sd00045
      Location:146 → 176
      ANK; ANK repeat [structural motif]
      cl27891
      Location:338 → 482
      LRR_3; Leucine Rich Repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08DV6.1 GenPept UniProtKB/Swiss-Prot:Q08DV6

    Gene LinkOut

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