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    TOR1AIP2 torsin 1A interacting protein 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 782450, updated on 30-Jan-2025

    Summary

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    Official Symbol
    TOR1AIP2provided by VGNC
    Official Full Name
    torsin 1A interacting protein 2provided by VGNC
    Primary source
    VGNC:VGNC:36225
    See related
    BGD:BT13256; EnsemblRapid:ENSBTAG00070011090 EnsemblRapid:ENSBTAG00070011100
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    IFRG15
    Orthologs
    human mouse all
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    Genomic context

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    See TOR1AIP2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 16 NC_037343.1 (61051235..61095817, complement)

    Chromosome 16 - NC_037343.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 163 member A Neighboring gene uncharacterized LOC112441913 Neighboring gene torsin 1A interacting protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene centrosomal protein 350 Neighboring gene uncharacterized LOC132342486

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037343.1 Chromosome 16 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC143037, MGC159772

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in membrane organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon alpha responsive; torsin A interacting protein 2
    Names
    interferon responsive gene 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099184.2 → NP_001092654.1  torsin A interacting protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer protein (torsin A interacting protein 2).
      Source sequence(s)
      BC142484, DY088204, DY153753
      UniProtKB/TrEMBL
      A0A3Q1M5S7, A5PKH0, F1N6U6
      Related
      ENSBTAP00070014821.1, ENSBTAT00070024976.1
      Conserved Domains (1) summary
      pfam05609
      Location:17 → 467
      LAP1C; Lamina-associated polypeptide 1C (LAP1C)

    2. NM_001105647.2 → NP_001099117.1  interferon alpha responsive isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) shares a portion of its 5' UTR, but not any coding sequence, with variant 1. Variant 2 encodes a distinct protein (interferon alpha responsive) compared to variant 1 (torsin A interacting protein 2).
      Source sequence(s)
      BC123781, DV894242, DY088204
      UniProtKB/TrEMBL
      A7YVI2
      Related
      ENSBTAP00070014840.1, ENSBTAT00070025000.1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037343.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      61051235..61095817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010813374.4 → XP_010811676.1  torsin A interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M5S7, A5PKH0, F1N6U6
      Conserved Domains (1) summary
      pfam05609
      Location:17 → 467
      LAP1C; Lamina-associated polypeptide 1C (LAP1C)

    2. XM_024976543.2 → XP_024832311.1  torsin A interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M5S7, A5PKH0, F1N6U6
      Conserved Domains (1) summary
      pfam05609
      Location:17 → 467
      LAP1C; Lamina-associated polypeptide 1C (LAP1C)

    3. XM_010813373.4 → XP_010811675.1  torsin A interacting protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M5S7, A5PKH0, F1N6U6
      Conserved Domains (1) summary
      pfam05609
      Location:17 → 467
      LAP1C; Lamina-associated polypeptide 1C (LAP1C)

    4. XM_059875573.1 → XP_059731556.1  interferon alpha responsive isoform X2

      UniProtKB/TrEMBL
      A7YVI2
      Related
      ENSBTAP00070014861.1, ENSBTAT00070025027.1
    Nucleotide Protein Strain
    Heading Accession and Version

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