LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: LYVE1provided by VGNC
Official Full Name: lymphatic vessel endothelial hyaluronan receptor 1provided by VGNC
Primary source: VGNC:VGNC:31116
See related: BGD:BT17439; EnsemblRapid:ENSBTAG00070028996
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: XLKD1; LYVE-1; CRSBP-1
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	15	NC_037342.1 (42102179..42116470)

Chromosome 15 - NC_037342.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CRSBP-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence.
Title: Cloning, expression, characterization, and role in autocrine cell growth of cell surface retention sequence binding protein-1.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hyaluronic acid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: lymphatic vessel endothelial hyaluronic acid receptor 1

Names: cell surface retention sequence binding protein-1; extracellular link domain containing 1; extracellular link domain-containing protein 1; lymphatic vessel endothelial HA recptor-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205815.2 → NP_991384.2 lymphatic vessel endothelial hyaluronic acid receptor 1 precursor

Status: PROVISIONAL

Source sequence(s)

BC140639

UniProtKB/Swiss-Prot

Q6UC88

UniProtKB/TrEMBL

A5D7P9

Related

ENSBTAP00070039991.1, ENSBTAT00070065919.1

Conserved Domains (1) summary

cd03516
Location:34 → 180

Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...