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    TSPAN18 tetraspanin 18 [ Bos taurus (domestic cattle) ]

    Gene ID: 783765, updated on 29-Jan-2025

    Summary

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    Official Symbol
    TSPAN18provided by VGNC
    Official Full Name
    tetraspanin 18provided by VGNC
    Primary source
    VGNC:VGNC:36433
    See related
    BGD:BT14443; Ensembl:ENSBTAG00000021484
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TSPAN18 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (74788741..75004308)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA61 Neighboring gene uncharacterized LOC112441654 Neighboring gene CD82 molecule Neighboring gene tumor protein p53 inducible protein 11 Neighboring gene PR/SET domain 11 Neighboring gene synaptotagmin 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tetraspanin-18
    Names
    tetraspanin similiar to uroplakin 1
    tspan-18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080920.1 → NP_001074389.1  tetraspanin-18

      See identical proteins and their annotated locations for NP_001074389.1

      Status: PROVISIONAL

      Source sequence(s)
      BT021809
      UniProtKB/Swiss-Prot
      Q58CY8
      UniProtKB/TrEMBL
      A0AAA9SWF8
      Related
      ENSBTAP00070041232.1, ENSBTAT00070067528.1
      Conserved Domains (1) summary
      cd03156
      Location:105 → 218
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      74788741..75004308
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059875002.1 → XP_059730985.1  tetraspanin-18 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S2H2, A0AAA9SBH5

    2. XM_024975564.2 → XP_024831332.1  tetraspanin-18 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S2H2, A0AAA9SBH5
      Related
      ENSBTAP00070041281.1, ENSBTAT00070067612.1
      Conserved Domains (1) summary
      cd03156
      Location:184 → 297
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

    3. XM_024975566.2 → XP_024831334.1  tetraspanin-18 isoform X2

      UniProtKB/TrEMBL
      A0AAA9SBH5
      Conserved Domains (1) summary
      cd03156
      Location:184 → 284
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

    4. XM_024975569.2 → XP_024831337.1  tetraspanin-18 isoform X3

      UniProtKB/Swiss-Prot
      Q58CY8
      UniProtKB/TrEMBL
      A0AAA9SWF8
      Conserved Domains (1) summary
      cd03156
      Location:105 → 218
      uroplakin_I_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), uroplakin_I_like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

    5. XM_059875003.1 → XP_059730986.1  tetraspanin-18 isoform X3

      UniProtKB/Swiss-Prot
      Q58CY8
      UniProtKB/TrEMBL
      A0AAA9SWF8

    6. XM_059875005.1 → XP_059730988.1  tetraspanin-18 isoform X3

      UniProtKB/Swiss-Prot
      Q58CY8
      UniProtKB/TrEMBL
      A0AAA9SWF8

    7. XM_059875004.1 → XP_059730987.1  tetraspanin-18 isoform X3

      UniProtKB/Swiss-Prot
      Q58CY8
      UniProtKB/TrEMBL
      A0AAA9SWF8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58CY8.1 GenPept UniProtKB/Swiss-Prot:Q58CY8

    Gene LinkOut

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    Research Materials