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    TNFSF13B TNF superfamily member 13b [ Bos taurus (domestic cattle) ]

    Gene ID: 504507, updated on 29-Jan-2025

    Summary

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    Official Symbol
    TNFSF13Bprovided by VGNC
    Official Full Name
    TNF superfamily member 13bprovided by VGNC
    Primary source
    VGNC:VGNC:107257
    See related
    Ensembl:ENSBTAG00000011563
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TNLG7A
    Orthologs
    human mouse all
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    Genomic context

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    See TNFSF13B in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 12 NC_037339.1 (83641493..83673073)

    Chromosome 12 - NC_037339.1Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 13 Neighboring gene DNA ligase 4 Neighboring gene myosin XVI Neighboring gene uncharacterized LOC132346799 Neighboring gene transfer RNA tyrosine (anticodon AUA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037339.1 Chromosome 12 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning, genomic organization and expression analysis of the gene encoding bovine (Bos taurus) B-cell activating factor belonging to the TNF family (BAFF). Guan ZB, et al. Gene, 2008 Dec 1. PMID 18786621
    2. Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. Premzl M. Immunogenetics, 2016 Feb. PMID 26646413
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables receptor ligand activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of B cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tumor necrosis factor ligand superfamily member 13B
    Names
    B-cell activating factor
    B-lymphocyte stimulator
    tumor necrosis factor (ligand) superfamily, member 13b
    tumor necrosis factor ligand 7A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114506.2 → NP_001107978.1  tumor necrosis factor ligand superfamily member 13B

      See identical proteins and their annotated locations for NP_001107978.1

      Status: VALIDATED

      Source sequence(s)
      NKLS02000012
      UniProtKB/TrEMBL
      B0LKN7, G3N0R8
      Related
      ENSBTAP00070014188.1, ENSBTAT00070023899.1
      Conserved Domains (1) summary
      cd00184
      Location:141 → 277
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037339.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      83641493..83673073
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015473938.3 → XP_015329424.2  tumor necrosis factor ligand superfamily member 13B isoform X1

      Conserved Domains (1) summary
      cd00184
      Location:140 → 276
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
    Nucleotide Protein Strain
    Heading Accession and Version

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