MT2A metallothionein 2A [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: MT2A
Gene description: metallothionein 2A
See related: BGD:BT12689; Ensembl:ENSBTAG00000023659
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as: MT2; MT-2; MT-II
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Genomic context

Location:: chromosome: 18

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	18	NC_037345.1 (24042365..24043331, complement)

Chromosome 18 - NC_037345.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

these results reveal that melatonin and MT2 are essential regulator of bovine granulosa cells function by modulating reproduction-related genes expression, hormones secretion and other regulators of folliculogenesis.
Title: The Mechanism of Melatonin and Its Receptor MT2 Involved in the Development of Bovine Granulosa Cells.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to cadmium ion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to copper ion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to zinc ion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in detoxification of copper ion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in intracellular zinc ion homeostasis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: metallothionein-2

Names: metallothionein 2 A; metallothionein-II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.