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    LDHD lactate dehydrogenase D [ Bos taurus (domestic cattle) ]

    Gene ID: 510284, updated on 29-Jan-2025

    Summary

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    Official Symbol
    LDHDprovided by VGNC
    Official Full Name
    lactate dehydrogenase Dprovided by VGNC
    Primary source
    VGNC:VGNC:30825
    See related
    BGD:BT19572; Ensembl:ENSBTAG00000006779
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LDHD in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (2453027..2458656, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 59 Neighboring gene uncharacterized LOC132342771 Neighboring gene zinc and ring finger 1 Neighboring gene ZFP1 zinc finger protein Neighboring gene uncharacterized LOC132342772

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC139689

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables D-lactate dehydrogenase (cytochrome) activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables D-lactate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lactate catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    probable D-lactate dehydrogenase, mitochondrial
    Names
    D-lactate dehydrogenase
    NP_001068911.1
    XP_005218396.1
    XP_059732596.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075443.1 → NP_001068911.1  probable D-lactate dehydrogenase, mitochondrial

      See identical proteins and their annotated locations for NP_001068911.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118204
      UniProtKB/TrEMBL
      A0AAA9SMC1, Q148K4
      Related
      ENSBTAP00070025601.1, ENSBTAT00070042821.1
      Conserved Domains (3) summary
      COG0277
      Location:34 → 482
      GlcD; FAD/FMN-containing dehydrogenase [Energy production and conversion]
      pfam01565
      Location:66 → 202
      FAD_binding_4; FAD binding domain
      pfam02913
      Location:243 → 482
      FAD-oxidase_C; FAD linked oxidases, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      2453027..2458656 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876613.1 → XP_059732596.1  probable D-lactate dehydrogenase, mitochondrial isoform X2

    2. XM_005218339.5 → XP_005218396.1  probable D-lactate dehydrogenase, mitochondrial isoform X1

      UniProtKB/TrEMBL
      A0AAA9SMC1
      Related
      ENSBTAP00070025589.1, ENSBTAT00070042807.1
      Conserved Domains (3) summary
      COG0277
      Location:34 → 484
      GlcD; FAD/FMN-containing dehydrogenase [Energy production and conversion]
      pfam01565
      Location:66 → 202
      FAD_binding_4; FAD binding domain
      pfam02913
      Location:243 → 483
      FAD-oxidase_C; FAD linked oxidases, C-terminal domain

    RNA

    1. XR_238225.5 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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