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    LONRF3 LON peptidase N-terminal domain and ring finger 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 508189, updated on 29-Jan-2025

    Summary

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    Official Symbol
    LONRF3provided by VGNC
    Official Full Name
    LON peptidase N-terminal domain and ring finger 3provided by VGNC
    Primary source
    VGNC:VGNC:30950
    See related
    BGD:BT24617; Ensembl:ENSBTAG00000002615
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See LONRF3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (3392171..3431577)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCHC-type containing 12 Neighboring gene uncharacterized LOC101904382 Neighboring gene uncharacterized LOC132344303 Neighboring gene cancer/testis antigen family 47 member C1 Neighboring gene KIAA1210

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    LON peptidase N-terminal domain and RING finger protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191134.1 → NP_001178063.1  LON peptidase N-terminal domain and RING finger protein 3

      See identical proteins and their annotated locations for NP_001178063.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000030
      UniProtKB/TrEMBL
      A0A3Q1M455, A0A3Q1MB86
      Related
      ENSBTAP00070034044.1, ENSBTAT00070057019.1
      Conserved Domains (6) summary
      cd00162
      Location:466 → 505
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl19481
      Location:566 → 657
      LON; Found in ATP-dependent protease La (LON)
      sd00006
      Location:243 → 271
      TPR; TPR repeat [structural motif]
      pfam02190
      Location:555 → 756
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      pfam13414
      Location:242 → 308
      TPR_11; TPR repeat
      cl17238
      Location:158 → 195
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      3392171..3431577
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024987830.2 → XP_024843598.1  LON peptidase N-terminal domain and RING finger protein 3 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M455
      Conserved Domains (6) summary
      sd00006
      Location:243 → 271
      TPR; TPR repeat [structural motif]
      cd16513
      Location:158 → 196
      RING1-HC_LONFs; RING finger 1, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
      cd16514
      Location:516 → 557
      RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
      cl19481
      Location:671 → 872
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      cl26005
      Location:243 → 358
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      cl28410
      Location:494 → 582
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

    2. XM_010821326.4 → XP_010819628.1  LON peptidase N-terminal domain and RING finger protein 3 isoform X3

      UniProtKB/TrEMBL
      A0A3Q1M455, G3X6C1
      Related
      ENSBTAP00070034041.1, ENSBTAT00070057012.1
      Conserved Domains (6) summary
      cd00162
      Location:518 → 557
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl19481
      Location:618 → 709
      LON; Found in ATP-dependent protease La (LON)
      sd00006
      Location:243 → 271
      TPR; TPR repeat [structural motif]
      pfam02190
      Location:607 → 808
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      pfam13414
      Location:242 → 308
      TPR_11; TPR repeat
      cl17238
      Location:158 → 195
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

    3. XM_024987831.2 → XP_024843599.1  LON peptidase N-terminal domain and RING finger protein 3 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M455
      Conserved Domains (6) summary
      sd00006
      Location:243 → 271
      TPR; TPR repeat [structural motif]
      cd16513
      Location:158 → 196
      RING1-HC_LONFs; RING finger 1, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
      cd16514
      Location:464 → 505
      RING2-HC_LONFs; RING finger 2, HC subclass, found in the LON peptidase N-terminal domain and RING finger proteins family
      cl19481
      Location:619 → 820
      LON_substr_bdg; ATP-dependent protease La (LON) substrate-binding domain
      cl26005
      Location:243 → 351
      PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
      cl28410
      Location:442 → 530
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

    4. XM_059883320.1 → XP_059739303.1  LON peptidase N-terminal domain and RING finger protein 3 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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