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    ZZEF1 zinc finger ZZ-type and EF-hand domain containing 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 508144, updated on 29-Jan-2025

    Summary

    Official Symbol
    ZZEF1provided by VGNC
    Official Full Name
    zinc finger ZZ-type and EF-hand domain containing 1provided by VGNC
    Primary source
    VGNC:VGNC:37396
    See related
    BGD:BT13218; Ensembl:ENSBTAG00000016316
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    See ZZEF1 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    55
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 19 NC_037346.1 (24615795..24710730, complement)

    Chromosome 19 - NC_037346.1Genomic Context describing neighboring genes Neighboring gene purinergic receptor P2X 1 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 Neighboring gene cytochrome b5 domain containing 2 Neighboring gene ankyrin repeat and FYVE domain containing 1

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037346.1 Chromosome 19 Reference ARS-UCD2.0 Primary Assembly

    Expression

    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    General protein information

    Preferred Names
    zinc finger ZZ-type and EF-hand domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001206129.3NP_001193058.3  zinc finger ZZ-type and EF-hand domain-containing protein 1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000019
      UniProtKB/TrEMBL
      E1BNA9
      Related
      ENSBTAP00070028667.1, ENSBTAT00070047930.1
      Conserved Domains (6) summary
      cd08667
      Location:251380
      APC10-ZZEF1; APC10/DOC1-like domain of uncharacterized Zinc finger ZZ-type and EF-hand domain-containing protein 1 (ZZEF1) and homologs
      cd00051
      Location:94141
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd02249
      Location:18301877
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cd02343
      Location:17811828
      ZZ_EF; Zinc finger, ZZ type. Zinc finger present in proteins with an EF_hand motif. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      cl00049
      Location:11191192
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      pfam04388
      Location:14751624
      Hamartin; Hamartin protein

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037346.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      24615795..24710730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010815902.4XP_010814204.2  zinc finger ZZ-type and EF-hand domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      E1BNA9
      Conserved Domains (7) summary
      cd08667
      Location:251380
      APC10-ZZEF1; APC10/DOC1-like domain of uncharacterized Zinc finger ZZ-type and EF-hand domain-containing protein 1 (ZZEF1) and homologs
      cd00051
      Location:94141
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd02249
      Location:18301877
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cd02343
      Location:17811828
      ZZ_EF; Zinc finger, ZZ type. Zinc finger present in proteins with an EF_hand motif. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      cl00049
      Location:11191192
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      pfam04388
      Location:14751624
      Hamartin; Hamartin protein
      cl25751
      Location:19682113
      DUF4045; Domain of unknown function (DUF4045)
    2. XM_005220201.5XP_005220258.2  zinc finger ZZ-type and EF-hand domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      E1BNA9
      Conserved Domains (7) summary
      cd08667
      Location:251380
      APC10-ZZEF1; APC10/DOC1-like domain of uncharacterized Zinc finger ZZ-type and EF-hand domain-containing protein 1 (ZZEF1) and homologs
      cd00051
      Location:94141
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cd02249
      Location:18311878
      ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
      cd02343
      Location:17821829
      ZZ_EF; Zinc finger, ZZ type. Zinc finger present in proteins with an EF_hand motif. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
      cl00049
      Location:11201193
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      pfam04388
      Location:14761625
      Hamartin; Hamartin protein
      cl25751
      Location:19692114
      DUF4045; Domain of unknown function (DUF4045)