U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    GAD1 glutamate decarboxylase 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 517552, updated on 27-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    GAD1provided by VGNC
    Official Full Name
    glutamate decarboxylase 1provided by VGNC
    Primary source
    VGNC:VGNC:29204
    See related
    BGD:BT14191; Ensembl:ENSBTAG00000007258
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See GAD1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (25604283..25644011, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene tousled like kinase 1 Neighboring gene uncharacterized LOC112442555 Neighboring gene small integral membrane protein 10-like protein 1 Neighboring gene golgi reassembly stacking protein 2 Neighboring gene glutamate rich 2 Neighboring gene Sp5 transcription factor

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Novel SNPs of the bovine GAD1/gad67 gene and their association with growth traits in three native Chinese cattle breeds. Li F, et al. Mol Biol Rep, 2010 Jan. PMID 19728158
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results suggest that the GAD1 gene is a strong candidate gene that affects growth traits in cattle.
      Title: Novel SNPs of the bovine GAD1/gad67 gene and their association with growth traits in three native Chinese cattle breeds.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC142602

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables glutamate decarboxylase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in gamma-aminobutyric acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic active zone IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    glutamate decarboxylase 1
    Names
    glutamate decarboxylase 1 (brain, 67kDa)
    glutamic acid decarboxylase 1
    NP_001069224.1
    XP_005202387.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075756.2 → NP_001069224.1  glutamate decarboxylase 1

      See identical proteins and their annotated locations for NP_001069224.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120278
      UniProtKB/Swiss-Prot
      Q0VCA1
      UniProtKB/TrEMBL
      A0AAA9SD93
      Related
      ENSBTAP00000009547.5, ENSBTAT00000009547.6
      Conserved Domains (1) summary
      pfam00282
      Location:144 → 518
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      25604283..25644011 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005202330.5 → XP_005202387.1  glutamate decarboxylase 1 isoform X1

      See identical proteins and their annotated locations for XP_005202387.1

      UniProtKB/Swiss-Prot
      Q0VCA1
      UniProtKB/TrEMBL
      A0AAA9SD93
      Conserved Domains (1) summary
      pfam00282
      Location:144 → 518
      Pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VCA1.1 GenPept UniProtKB/Swiss-Prot:Q0VCA1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.