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    AGGF1 angiogenic factor with G-patch and FHA domains 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 511650, updated on 1-Jan-2025

    Summary

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    Official Symbol
    AGGF1provided by VGNC
    Official Full Name
    angiogenic factor with G-patch and FHA domains 1provided by VGNC
    Primary source
    VGNC:VGNC:25727
    See related
    BGD:BT20144; Ensembl:ENSBTAG00000034823
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    VG5Q
    Orthologs
    human mouse all
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    Genomic context

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    See AGGF1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (8176676..8223030)

    Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene ZZ-type zinc finger-containing protein 3-like Neighboring gene corticotropin releasing hormone binding protein Neighboring gene uncharacterized LOC107132813 Neighboring gene small nucleolar RNA SNORA47 Neighboring gene zinc finger BED-type containing 3 Neighboring gene phosphodiesterase 8B Neighboring gene small nucleolar RNA SNORA41

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC157060

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    angiogenic factor with G patch and FHA domains 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075532.2 → NP_001069000.2  angiogenic factor with G patch and FHA domains 1

      See identical proteins and their annotated locations for NP_001069000.2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000010
      UniProtKB/TrEMBL
      F1MKY1
      Related
      ENSBTAP00000046195.2, ENSBTAT00000049280.3
      Conserved Domains (4) summary
      COG1716
      Location:422 → 510
      FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
      cd00060
      Location:408 → 514
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam01585
      Location:618 → 659
      G-patch; G-patch domain
      cd16164
      Location:198 → 251
      OCRE_VG5Q; OCRE domain found in angiogenic factor VG5Q and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      8176676..8223030
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024997451.2 → XP_024853219.1  angiogenic factor with G patch and FHA domains 1 isoform X1

      Conserved Domains (3) summary
      cd00060
      Location:408 → 514
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd16164
      Location:198 → 251
      OCRE_VG5Q; OCRE domain found in angiogenic factor VG5Q and similar proteins
      pfam05335
      Location:29 → 78
      DUF745; Protein of unknown function (DUF745)
    Nucleotide Protein Strain
    Heading Accession and Version

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