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    WDFY4 WDFY family member 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 527790, updated on 29-Jan-2025

    Summary

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    Official Symbol
    WDFY4provided by VGNC
    Official Full Name
    WDFY family member 4provided by VGNC
    Primary source
    VGNC:VGNC:55999
    See related
    BGD:BT28308; Ensembl:ENSBTAG00000023028
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See WDFY4 in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    66
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 28 NC_037355.1 (43020261..43268439)

    Chromosome 28 - NC_037355.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 8 Neighboring gene Rho GTPase activating protein 22 Neighboring gene uncharacterized LOC132344153 Neighboring gene leucine rich repeat containing 18 Neighboring gene V-set and transmembrane domain containing 4 Neighboring gene family with sequence similarity 170 member B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037355.1 Chromosome 28 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    WD repeat- and FYVE domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205945.3 → NP_001192874.3  WD repeat- and FYVE domain-containing protein 4

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000028
      UniProtKB/TrEMBL
      F1MG90
      Related
      ENSBTAP00070023500.1, ENSBTAT00070039903.1
      Conserved Domains (4) summary
      cd01201
      Location:2391 → 2515
      PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
      sd00039
      Location:2939 → 2983
      7WD40; WD40 repeat [structural motif]
      pfam02138
      Location:2543 → 2824
      Beach; Beige/BEACH domain
      cl25539
      Location:2924 → 3185
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037355.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43020261..43268439
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024986689.2 → XP_024842457.1  WD repeat- and FYVE domain-containing protein 4 isoform X1

      Conserved Domains (4) summary
      cd01201
      Location:2416 → 2540
      PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
      sd00039
      Location:2964 → 3008
      7WD40; WD40 repeat [structural motif]
      pfam02138
      Location:2568 → 2849
      Beach; Beige/BEACH domain
      cl25539
      Location:2949 → 3210
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_024986690.2 → XP_024842458.1  WD repeat- and FYVE domain-containing protein 4 isoform X2

      Conserved Domains (4) summary
      cd01201
      Location:2416 → 2540
      PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
      sd00039
      Location:2957 → 3001
      7WD40; WD40 repeat [structural motif]
      pfam02138
      Location:2568 → 2849
      Beach; Beige/BEACH domain
      cl25539
      Location:2942 → 3203
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. XM_005226581.5 → XP_005226638.2  WD repeat- and FYVE domain-containing protein 4 isoform X3

      UniProtKB/TrEMBL
      F1MG90
      Conserved Domains (4) summary
      cd01201
      Location:2391 → 2515
      PH_BEACH; Pleckstrin homology domain in BEACH domain containing proteins
      sd00039
      Location:2939 → 2983
      7WD40; WD40 repeat [structural motif]
      pfam02138
      Location:2543 → 2824
      Beach; Beige/BEACH domain
      cl25539
      Location:2924 → 3185
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    4. XM_059882534.1 → XP_059738517.1  WD repeat- and FYVE domain-containing protein 4 isoform X4

    5. XM_059882535.1 → XP_059738518.1  WD repeat- and FYVE domain-containing protein 4 isoform X5

    6. XM_059882536.1 → XP_059738519.1  WD repeat- and FYVE domain-containing protein 4 isoform X6

    7. XM_059882537.1 → XP_059738520.1  WD repeat- and FYVE domain-containing protein 4 isoform X7

    8. XM_059882538.1 → XP_059738521.1  WD repeat- and FYVE domain-containing protein 4 isoform X8

    RNA

    1. XR_009493217.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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