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    HIP1 huntingtin interacting protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 505919, updated on 29-Jan-2025

    Summary

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    Official Symbol
    HIP1provided by VGNC
    Official Full Name
    huntingtin interacting protein 1provided by VGNC
    Primary source
    VGNC:VGNC:29857
    See related
    BGD:BT21860; Ensembl:ENSBTAG00000000781
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See HIP1 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 25 NC_037352.1 (33878188..34015891, complement)

    Chromosome 25 - NC_037352.1Genomic Context describing neighboring genes Neighboring gene POM121 transmembrane nucleoporin C Neighboring gene NOP2/Sun RNA methyltransferase 5 Neighboring gene uncharacterized LOC104975906 Neighboring gene microRNA mir-3432a-2 Neighboring gene C-C motif chemokine ligand 26 Neighboring gene C-C motif chemokine ligand 24

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037352.1 Chromosome 25 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables clathrin adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables clathrin light chain binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,4-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylinositol-3,5-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in clathrin coat assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cortical patch IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in clathrin-coated vesicle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    huntingtin-interacting protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192078.1 → NP_001179007.1  huntingtin-interacting protein 1

      See identical proteins and their annotated locations for NP_001179007.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000025
      UniProtKB/TrEMBL
      A0AAA9TRE6
      Related
      ENSBTAP00070031259.1, ENSBTAT00070052059.1
      Conserved Domains (4) summary
      smart00307
      Location:814 → 1012
      ILWEQ; I/LWEQ domain
      pfam07651
      Location:39 → 307
      ANTH; ANTH domain
      pfam16515
      Location:482 → 580
      HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
      cl25732
      Location:398 → 641
      SMC_N; RecF/RecN/SMC N terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037352.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      33878188..34015891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059881201.1 → XP_059737184.1  huntingtin-interacting protein 1 isoform X9

      UniProtKB/TrEMBL
      A0AAA9TRE6

    2. XM_059881200.1 → XP_059737183.1  huntingtin-interacting protein 1 isoform X8

      UniProtKB/TrEMBL
      A0AAA9TRE6

    3. XM_010819489.4 → XP_010817791.1  huntingtin-interacting protein 1 isoform X11

      UniProtKB/TrEMBL
      A0AAA9TRE6
      Conserved Domains (5) summary
      smart00307
      Location:815 → 1013
      ILWEQ; I/LWEQ domain
      pfam07651
      Location:37 → 307
      ANTH; ANTH domain
      pfam15619
      Location:390 → 551
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
      pfam16515
      Location:483 → 581
      HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
      cl23720
      Location:391 → 494
      RILP-like; Rab interacting lysosomal protein-like 1 and 2 (Rilpl1 and Rilpl2)

    4. XM_059881194.1 → XP_059737177.1  huntingtin-interacting protein 1 isoform X2

    5. XM_059881196.1 → XP_059737179.1  huntingtin-interacting protein 1 isoform X4

      UniProtKB/TrEMBL
      A0AAA9TRE6

    6. XM_059881199.1 → XP_059737182.1  huntingtin-interacting protein 1 isoform X7

    7. XM_059881193.1 → XP_059737176.1  huntingtin-interacting protein 1 isoform X1

    8. XM_059881195.1 → XP_059737178.1  huntingtin-interacting protein 1 isoform X3

      UniProtKB/TrEMBL
      A0AAA9TRE6

    9. XM_024984708.2 → XP_024840476.1  huntingtin-interacting protein 1 isoform X12

      UniProtKB/TrEMBL
      A0AAA9TRE6
      Conserved Domains (4) summary
      smart00307
      Location:814 → 1012
      ILWEQ; I/LWEQ domain
      pfam07651
      Location:39 → 307
      ANTH; ANTH domain
      pfam16515
      Location:482 → 580
      HIP1_clath_bdg; Clathrin-binding domain of Huntingtin-interacting protein 1
      cl25732
      Location:398 → 641
      SMC_N; RecF/RecN/SMC N terminal domain

    10. XM_059881198.1 → XP_059737181.1  huntingtin-interacting protein 1 isoform X6

      UniProtKB/TrEMBL
      A0AAA9TRE6

    11. XM_059881197.1 → XP_059737180.1  huntingtin-interacting protein 1 isoform X5

      UniProtKB/TrEMBL
      A0AAA9TRE6
      Related
      ENSBTAP00070031248.1, ENSBTAT00070052041.1

    12. XM_059881202.1 → XP_059737185.1  huntingtin-interacting protein 1 isoform X10

      UniProtKB/TrEMBL
      A0AAA9TRE6
    Nucleotide Protein Strain
    Heading Accession and Version

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