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    CYTH4 cytohesin 4 [ Bos taurus (domestic cattle) ]

    Gene ID: 517887, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CYTH4provided by VGNC
    Official Full Name
    cytohesin 4provided by VGNC
    Primary source
    VGNC:VGNC:49055
    See related
    BGD:BT28771; Ensembl:ENSBTAG00000014237
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PSCD4
    Orthologs
    human mouse all
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    Genomic context

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    See CYTH4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (75703704..75734565)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 6 Neighboring gene somatostatin receptor 3 Neighboring gene Rac family small GTPase 2 Neighboring gene microRNA mir-1835 Neighboring gene extracellular leucine rich repeat and fibronectin type III domain containing 2 Neighboring gene MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytohesin-4
    Names
    pleckstrin homology, Sec7 and coiled-coil domains 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256669.1 → NP_001243598.1  cytohesin-4

      See identical proteins and their annotated locations for NP_001243598.1

      Status: VALIDATED

      Source sequence(s)
      AW668721, EE970251, EE970916
      UniProtKB/TrEMBL
      F1ML63, F1N082
      Related
      ENSBTAP00000030414.4, ENSBTAT00000030432.4
      Conserved Domains (2) summary
      cd01252
      Location:258 → 376
      PH_GRP1-like; General Receptor for Phosphoinositides-1-like Pleckstrin homology (PH) domain
      pfam01369
      Location:61 → 243
      Sec7; Sec7 domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      75703704..75734565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991736.2 → XP_024847504.1  cytohesin-4 isoform X1

      UniProtKB/TrEMBL
      F1ML63
      Conserved Domains (2) summary
      cd01252
      Location:201 → 319
      PH_GRP1-like; General Receptor for Phosphoinositides-1-like Pleckstrin homology (PH) domain
      pfam01369
      Location:4 → 186
      Sec7; Sec7 domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001035321.1: Suppressed sequence

      Description
      NM_001035321.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.

    2. NM_001113300.1: Suppressed sequence

      Description
      NM_001113300.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein Strain
    Heading Accession and Version

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