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    CRTAC1 cartilage acidic protein 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 100139581, updated on 29-Jan-2025

    Summary

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    Official Symbol
    CRTAC1provided by VGNC
    Official Full Name
    cartilage acidic protein 1provided by VGNC
    Primary source
    VGNC:VGNC:27725
    See related
    BGD:BT18699; Ensembl:ENSBTAG00000008102
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CRTAC1 in Genome Data Viewer
    Location:
    chromosome: 26
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 26 NC_037353.1 (19019143..19170819, complement)

    Chromosome 26 - NC_037353.1Genomic Context describing neighboring genes Neighboring gene secreted frizzled related protein 5 Neighboring gene uncharacterized LOC101905123 Neighboring gene golgin A7 family member B Neighboring gene R3H domain and coiled-coil containing 1 like Neighboring gene lysyl oxidase like 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037353.1 Chromosome 26 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axonal fasciculation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cartilage acidic protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191289.2 → NP_001178218.2  cartilage acidic protein 1 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AAFC03054762, AAFC03124199, AAFC03124200, AAFC03125898
      UniProtKB/TrEMBL
      A0AAA9THC0
      Related
      ENSBTAP00070041653.1, ENSBTAT00070068172.1
      Conserved Domains (3) summary
      pfam07593
      Location:460 → 512
      UnbV_ASPIC; ASPIC and UnbV
      pfam07645
      Location:559 → 605
      EGF_CA; Calcium-binding EGF domain
      pfam13517
      Location:299 → 363
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    2. NM_001205325.1 → NP_001192254.1  cartilage acidic protein 1 isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains a distinct 3' terminal coding exon and UTR, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AAFC03054762, AAFC03124199, AAFC03124200, AAFC03125898
      UniProtKB/TrEMBL
      A0A3Q1LN98, A0AAA9THC0
      Related
      ENSBTAP00070041639.1, ENSBTAT00070068153.1
      Conserved Domains (3) summary
      pfam07593
      Location:460 → 512
      UnbV_ASPIC; ASPIC and UnbV
      pfam07645
      Location:559 → 605
      EGF_CA; Calcium-binding EGF domain
      pfam13517
      Location:299 → 363
      VCBS; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037353.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      19019143..19170819 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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