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    CCNE1 cyclin E1 [ Bos taurus (domestic cattle) ]

    Gene ID: 533526, updated on 1-Jan-2025

    Summary

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    Official Symbol
    CCNE1provided by VGNC
    Official Full Name
    cyclin E1provided by VGNC
    Primary source
    VGNC:VGNC:26966
    See related
    BGD:BT28086; Ensembl:ENSBTAG00000004735
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See CCNE1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (40423660..40435547)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology and FYVE domain containing 1 Neighboring gene microRNA mir-2901 Neighboring gene chromosome 18 C19orf12 homolog Neighboring gene URI1 prefoldin like chaperone Neighboring gene uncharacterized LOC104974829

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of cyclin E1-CDK2 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    G1/S-specific cyclin-E1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192776.1 → NP_001179705.1  G1/S-specific cyclin-E1

      See identical proteins and their annotated locations for NP_001179705.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/TrEMBL
      A0A3Q1NCH0
      Related
      ENSBTAP00000069087.2, ENSBTAT00000081864.2
      Conserved Domains (2) summary
      pfam00134
      Location:116 → 243
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:246 → 364
      Cyclin_C; Cyclin, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      40423660..40435547
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024978360.2 → XP_024834128.1  G1/S-specific cyclin-E1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1NCH0
      Conserved Domains (2) summary
      pfam00134
      Location:116 → 243
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:246 → 364
      Cyclin_C; Cyclin, C-terminal domain

    2. XM_024978361.2 → XP_024834129.1  G1/S-specific cyclin-E1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1NCH0
      Conserved Domains (2) summary
      pfam00134
      Location:116 → 237
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:262 → 344
      Cyclin_C; Cyclin, C-terminal domain
    Nucleotide Protein Strain
    Heading Accession and Version

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