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    USP10 ubiquitin specific peptidase 10 [ Bos taurus (domestic cattle) ]

    Gene ID: 510164, updated on 29-Jan-2025

    Summary

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    Official Symbol
    USP10provided by VGNC
    Official Full Name
    ubiquitin specific peptidase 10provided by VGNC
    Primary source
    VGNC:VGNC:36710
    See related
    BGD:BT25562; Ensembl:ENSBTAG00000009446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See USP10 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (10870728..10933882)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 36 Neighboring gene uncharacterized LOC104974744 Neighboring gene transfer RNA histidin (anticodon GUG) Neighboring gene cysteine rich secretory protein LCCL domain containing 2 Neighboring gene uncharacterized LOC112442263 Neighboring gene transfer RNA serine (anticodon GGA)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC143261

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cysteine-type deubiquitinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA damage response, signal transduction by p53 class mediator IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein deubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of autophagy IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in early endosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ubiquitin carboxyl-terminal hydrolase 10
    Names
    deubiquitinating enzyme 10
    ubiquitin thioesterase 10
    ubiquitin thiolesterase 10
    ubiquitin-specific-processing protease 10
    NP_001092394.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001098924.1 → NP_001092394.1  ubiquitin carboxyl-terminal hydrolase 10

      See identical proteins and their annotated locations for NP_001092394.1

      Status: PROVISIONAL

      Source sequence(s)
      BC142223
      UniProtKB/Swiss-Prot
      A5PJS6
      UniProtKB/TrEMBL
      A0AAA9TB10
      Related
      ENSBTAP00070045128.1, ENSBTAT00070074074.1
      Conserved Domains (2) summary
      cd02257
      Location:522 → 795
      Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
      pfam00443
      Location:416 → 794
      UCH; Ubiquitin carboxyl-terminal hydrolase

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      10870728..10933882
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A5PJS6.1 GenPept UniProtKB/Swiss-Prot:A5PJS6

    Gene LinkOut

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