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    SF3B1 splicing factor 3b subunit 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 510177, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SF3B1provided by VGNC
    Official Full Name
    splicing factor 3b subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:34509
    See related
    BGD:BT11693; Ensembl:ENSBTAG00000008915
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SF3B1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 2 NC_037329.1 (85946144..85984071, complement)

    Chromosome 2 - NC_037329.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112443640 Neighboring gene growth differentiation factor 3 pseudogene Neighboring gene coenzyme Q10B Neighboring gene U6 spliceosomal RNA Neighboring gene heat shock protein family D (Hsp60) member 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037329.1 Chromosome 2 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in spliceosomal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U12-type spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of U2 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of U2-type prespliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    splicing factor 3B subunit 1
    Names
    splicing factor 3b, subunit 1, 155kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192994.1 → NP_001179923.1  splicing factor 3B subunit 1

      See identical proteins and their annotated locations for NP_001179923.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000002
      UniProtKB/TrEMBL
      A0AAA9TIM0, F1MX61
      Related
      ENSBTAP00000011734.5, ENSBTAT00000011734.6
      Conserved Domains (4) summary
      smart01104
      Location:241 → 382
      CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
      COG5181
      Location:462 → 1304
      HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
      sd00044
      Location:850 → 874
      HEAT; HEAT repeat [structural motif]
      pfam08920
      Location:332 → 442
      SF3b1; Splicing factor 3B subunit 1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037329.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      85946144..85984071 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059892869.1 → XP_059748852.1  splicing factor 3B subunit 1 isoform X1

      UniProtKB/TrEMBL
      A0AAA9TIM0

    2. XM_025000534.2 → XP_024856302.1  splicing factor 3B subunit 1 isoform X2

      UniProtKB/TrEMBL
      A0AAA9TIM0
      Conserved Domains (4) summary
      smart01104
      Location:75 → 216
      CTD; Spt5 C-terminal nonapeptide repeat binding Spt4
      COG5181
      Location:296 → 1138
      HSH155; U2 snRNP spliceosome subunit [RNA processing and modification]
      sd00044
      Location:684 → 708
      HEAT; HEAT repeat [structural motif]
      pfam08920
      Location:166 → 277
      SF3b1; Splicing factor 3B subunit 1

    3. XM_059892878.1 → XP_059748861.1  splicing factor 3B subunit 1 isoform X4

    4. XM_059892873.1 → XP_059748856.1  splicing factor 3B subunit 1 isoform X3

    5. XM_059892891.1 → XP_059748874.1  splicing factor 3B subunit 1 isoform X5

      UniProtKB/TrEMBL
      A0AAA9RV26, A0AAA9T818

    6. XM_059892883.1 → XP_059748866.1  splicing factor 3B subunit 1 isoform X5

      UniProtKB/TrEMBL
      A0AAA9RV26, A0AAA9T818
      Related
      ENSBTAP00000076077.1, ENSBTAT00000126974.1
    Nucleotide Protein Strain
    Heading Accession and Version

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