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    TLCD5 TLC domain containing 5 [ Bos taurus (domestic cattle) ]

    Gene ID: 520468, updated on 29-Jan-2025

    Summary

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    Official Symbol
    TLCD5provided by VGNC
    Official Full Name
    TLC domain containing 5provided by VGNC
    Primary source
    VGNC:VGNC:35970
    See related
    BGD:BT27435; Ensembl:ENSBTAG00000021342
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TMEM136
    Orthologs
    human mouse all
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    Genomic context

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    See TLCD5 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (30911338..30918654)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene POU class 2 homeobox 3 Neighboring gene out at first homolog Neighboring gene Rho guanine nucleotide exchange factor 12 Neighboring gene uncharacterized LOC132342319 Neighboring gene glutamate ionotropic receptor kainate type subunit 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC139257

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TLC domain-containing protein 5
    Names
    transmembrane protein 136

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075806.1 → NP_001069274.1  TLC domain-containing protein 5

      See identical proteins and their annotated locations for NP_001069274.1

      Status: PROVISIONAL

      Source sequence(s)
      BC119842
      UniProtKB/Swiss-Prot
      Q0VD42
      Conserved Domains (1) summary
      smart00724
      Location:29 → 225
      TLC; TRAM, LAG1 and CLN8 homology domains

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      30911338..30918654
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005215960.5 → XP_005216017.1  TLC domain-containing protein 5 isoform X1

      See identical proteins and their annotated locations for XP_005216017.1

      UniProtKB/Swiss-Prot
      Q0VD42
      Related
      ENSBTAP00070015579.1, ENSBTAT00070026122.1
      Conserved Domains (1) summary
      smart00724
      Location:29 → 225
      TLC; TRAM, LAG1 and CLN8 homology domains

    2. XM_005215961.5 → XP_005216018.1  TLC domain-containing protein 5 isoform X1

      See identical proteins and their annotated locations for XP_005216018.1

      UniProtKB/Swiss-Prot
      Q0VD42
      Conserved Domains (1) summary
      smart00724
      Location:29 → 225
      TLC; TRAM, LAG1 and CLN8 homology domains

    3. XM_005215958.5 → XP_005216015.1  TLC domain-containing protein 5 isoform X1

      See identical proteins and their annotated locations for XP_005216015.1

      UniProtKB/Swiss-Prot
      Q0VD42
      Conserved Domains (1) summary
      smart00724
      Location:29 → 225
      TLC; TRAM, LAG1 and CLN8 homology domains

    4. XM_005215963.5 → XP_005216020.1  TLC domain-containing protein 5 isoform X2

      See identical proteins and their annotated locations for XP_005216020.1

      Conserved Domains (1) summary
      cl02759
      Location:1 → 124
      TRAM_LAG1_CLN8; TLC domain

    5. XM_005215962.5 → XP_005216019.1  TLC domain-containing protein 5 isoform X1

      See identical proteins and their annotated locations for XP_005216019.1

      UniProtKB/Swiss-Prot
      Q0VD42
      Conserved Domains (1) summary
      smart00724
      Location:29 → 225
      TLC; TRAM, LAG1 and CLN8 homology domains
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VD42.1 GenPept UniProtKB/Swiss-Prot:Q0VD42

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